Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Betaine SCHEMBL8018563 | 0.90 | LMNA (0.37) | USP2HTTLPAR5CYP1A2CYP3A4 | |
| SCHEMBL17995076 | 0.87 | USP2 (0.50) | USP2HTTLPAR5CYP1A2CYP3A4 | |
| SCHEMBL6235780 | 0.87 | USP2 (0.41) | USP2HTTLPAR5CYP1A2CYP3A4 | |
| SCHEMBL28643334 | 0.85 | USP2 (0.49) | USP2HTTLPAR5CYP1A2CYP3A4 | |
| Betaine SCHEMBL8034210 | 0.85 | USP2 (0.43) | USP2HTTLPAR5CYP1A2CYP3A4 | |
| SCHEMBL3813244 | 0.82 | USP2 (0.58) | USP2HTTLPAR5CYP1A2CYP3A4 | |
| SCHEMBL10395669 | 0.81 | USP2 (0.61) | USP2HTTLPAR5CYP1A2CYP3A4 | |
| SCHEMBL9854730 | 0.81 | USP2 (0.56) | USP2HTTLPAR5CYP1A2CYP3A4 | |
| SCHEMBL11146470 | 0.79 | PSMD14 (0.43) | USP2HTTLPAR5CYP1A2CYP3A4 | |
| SCHEMBL17991834 | 0.79 | PSMD14 (0.47) | HTTPSMD14PLA2G1BMMP2ATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004771-A | EXTRACTED MYCOBACTERIAL SAMPLE IS SUITABLE FOR DETECTION BY CULTURE AND AMPLIFICATION | INTEGRATED RESEARCH TECHNOLOGY, LLC (US) | 1999-12-21 | — | — | US | disclosed |
| US-5658749-A | DECREASING THE BUOYANCY OF MICROORGANISMS CONTAINING MYCOLIC ACID-LIKE STRUCTURES IN THE OUTER MEMBRANE USING A SOLUTION OF AN SB-18-LIKE OR ROD-LIKE DETERGENT; AMPHOTERIC SURFACTANTS; MEDICAL DIAGNOSIS; CULTURES; AMPLIFICATION | CORNING CLINICAL LABORATORIES, INC. (US) | 1997-08-19 | — | — | US | disclosed |