Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGPL1 | O95470 | 4/20 | 0.55 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.55 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.55 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.55 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.54 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.51 |
| ▸ | FDPS | P14324 | 3/20 | 0.50 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.50 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29068432 | 1.00 | SGPL1 (0.55) | SGPL1LPAR3LPAR1LPAR2SMPD1 | |
| SCHEMBL8436033 | 0.92 | LPAR5 (0.49) | SGPL1LPAR3LPAR1LPAR2SMPD1 | |
| SCHEMBL31325199 | 0.91 | PLA2G4A (0.51) | SGPL1LPAR3SMPD1LPAR5PLA2G4A | |
| SCHEMBL8433415 | 0.89 | FDPS (0.50) | SGPL1LPAR3LPAR1LPAR2SMPD1 | |
| SCHEMBL8437881 | 0.85 | CYP3A4 (0.53) | SGPL1LPAR3LPAR1SMPD1FDPS | |
| SCHEMBL2476420 | 0.84 | LPAR5 (0.43) | SGPL1LPAR3LPAR1LPAR2LPAR5 | |
| SCHEMBL11150984 | 0.84 | LPAR3 (0.63) | SGPL1LPAR3LPAR1LPAR2SMPD1 | |
| SCHEMBL10661398 | 0.84 | LPAR3 (0.75) | LPAR3LPAR1LPAR2SMPD1LPAR5 | |
| SCHEMBL30148485 | 0.84 | LPAR3 (0.63) | SGPL1LPAR3LPAR1LPAR2SMPD1 | |
| SCHEMBL28839224 | 0.84 | LPAR3 (0.63) | SGPL1LPAR3LPAR1LPAR2SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110655546-B | Sofosbuvir derivative, and preparation method and application thereof | 安徽贝克制药股份有限公司 | 2023-05-16 | — | — | CN | disclosed |
| US-5922654-A | TWO OR MORE ORGANOMETALLIC COMPOUNDS WHERE THE METAL IS A TRANSITION METAL OR SEMIMETAL, OR ZINC; FOR EXAMPLE, ZINC DIALKYLDITHIOPHOSPHATE, OR NICKEL DIALKYLDITHIOCARBAMATE; HIGHER LOAD BEARING PROPERTIES, HIGH TEMPERATURE PERFORMANCE | NSK LTD. (JP) | 1999-07-13 | — | — | US | disclosed |