SCHEMBL8436879

SCHEMBL8436879

C=Cc1ccc(CSCCOC(=O)CCC(=O)O)cc1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.44
PTGER1 P34995 1/20 0.37
PTGER4 P35408 1/20 0.37
PTGER3 P43115 1/20 0.37
PTGER2 P43116 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
HTT P42858 1/20 0.35
NPC1 O15118 1/20 0.34
GSTP1 P09211 1/20 0.33
GSTM2 P28161 1/20 0.33
FOLH1 Q04609 2/20 0.33
PPARA Q07869 2/20 0.33
ALDH1A1 P00352 3/20 0.33
HPGD P15428 3/20 0.33
FFAR4 Q5NUL3 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
APP P05067 1/20 0.31
FFAR1 O14842 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8745145 0.95 CYP2C19 (0.40) CYP2C19PTGER1PTGER4PTGER3PTGER2
SCHEMBL8436342 0.94 CYP2C19 (0.43) CYP2C19PTGER1PTGER4PTGER3PTGER2
SCHEMBL8745101 0.85 CYP2C19 (0.36) CYP2C19PTGER1PTGER4PTGER3PTGER2
SCHEMBL13696521 0.83 CYP2C19 (0.65) CYP2C19PTGER1PTGER4PTGER3PTGER2
SCHEMBL5674593 0.83 CYP2C19 (0.64) CYP2C19PTGER1PTGER4PTGER3PTGER2
SCHEMBL13696520 0.81 CYP2C19 (0.43) CYP2C19PTGER1PTGER4PTGER3PTGER2
Glycolic Acid SCHEMBL8745106 0.81 CYP2C19 (0.37) CYP2C19PTGER1PTGER4PTGER3PTGER2
SCHEMBL8436340 0.79 MEN1 (0.43) HTTALDH1A1FFAR4MEN1KMT2A
SCHEMBL14557984 0.78 TDP1 (0.41) TDP1NPC1PPARAFFAR4APP
SCHEMBL8433057 0.78 CHRNB2 (0.34) CYP2C19TDP1ALDH1A1HPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0466220-B1 Carboxy containing monomers and polymers and latices prepared from same JOHNSON & JOHNSON CLIN DIAG (US) 1997-01-29 EP claimed
EP-0462670-B1 Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to caboxylated particles & a kit containing same JOHNSON & JOHNSON CLIN DIAG (US) 1996-08-21 EP claimed
EP-0462644-B1 Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use JOHNSON & JOHNSON CLIN DIAG (US) 1995-10-18 EP claimed
US-5278267-A Water insoluble vinyl aromatic polymer EASTMAN KODAK COMPANY (US) 1994-01-11 US claimed
US-5210289-A Homo or coploymers for medical diagnosis EASTMAN KODAK COMPANY (US) 1993-05-11 US claimed
US-5155166-A Diagnostic kits for detecting antibodies or antigens; reacting active amine- or sulfhydryl-containing compound with quaternized carboxylic polymers EASTMAN KODAK COMPANY (US) 1992-10-13 US claimed
US-5149737-A Carboxy group extended from polymer surface allows easier attachment of biological substances EASTMAN KODAK COMPANY (US) 1992-09-22 US claimed
US-5147777-A Analysis, diagnosis EASTMAN KODAK COMPANY (US) 1992-09-15 US claimed
EP-0466220-A2 Carboxy containing monomers and polymers and latices prepared from same Johnson & Johnson Clinical Diagnostics, Inc. (US) 1992-01-15 EP claimed
EP-0462670-A1 Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to caboxylated particles & a kit containing same Johnson & Johnson Clinical Diagnostics, Inc. (US) 1991-12-27 EP claimed
EP-0462644-A1 Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use Johnson & Johnson Clinical Diagnostics, Inc. (US) 1991-12-27 EP claimed
US-5888723-A SENSITIVE HYBRIDIZATION ASSAY USING NUCLEIC ACID REAGENT COMPOSED OF OLIGONUCLEOTIDES COVALENTLY ATTACHED TO POLYMER PARTICLES WHICH ARE ADHERED TO SUPPORT USING WATER INSOLUBLE ADHESIVE; LOW BACKGROUND JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1999-03-30 US disclosed
EP-0466220-B1 Carboxy containing monomers and polymers and latices prepared from same JOHNSON & JOHNSON CLIN DIAG (US) 1997-01-29 EP disclosed
EP-0462670-B1 Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to caboxylated particles & a kit containing same JOHNSON & JOHNSON CLIN DIAG (US) 1996-08-21 EP disclosed
EP-0530357-B1 ELEMENT AND METHOD FOR NUCLEIC ACID AMPLIFICATION AND DETECTION USING ADHERED PROBES JOHNSON & JOHNSON CLIN DIAG (US) 1995-11-15 EP disclosed
US-5147777-A Analysis, diagnosis EASTMAN KODAK COMPANY (US) 1992-09-15 US disclosed
EP-0468585-A2 Biologically active reagent, analytical element and methods for use of the reagent Johnson & Johnson Clinical Diagnostics, Inc. (US) 1992-01-29 EP disclosed
EP-0466220-A2 Carboxy containing monomers and polymers and latices prepared from same Johnson & Johnson Clinical Diagnostics, Inc. (US) 1992-01-15 EP disclosed
EP-0462670-A1 Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to caboxylated particles & a kit containing same Johnson & Johnson Clinical Diagnostics, Inc. (US) 1991-12-27 EP disclosed
EP-0462644-A1 Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use Johnson & Johnson Clinical Diagnostics, Inc. (US) 1991-12-27 EP disclosed