Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.33 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.33 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.33 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8436879 | 0.94 | CYP2C19 (0.44) | CYP2C19NPC1PPARAPTGER1PTGER4 | |
| SCHEMBL8745145 | 0.89 | CYP2C19 (0.40) | CYP2C19NPC1PPARAPTGER1PTGER4 | |
| SCHEMBL8745101 | 0.84 | CYP2C19 (0.36) | CYP2C19PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL5674593 | 0.82 | CYP2C19 (0.64) | CYP2C19PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL18868398 | 0.81 | TDP1 (0.45) | NPC1PPARATDP1ALBCYP4Z1 | |
| SCHEMBL8435267 | 0.81 | HTT (0.42) | NPC1PPARAALBALDH1A1HTT | |
| Glycolic Acid SCHEMBL8745106 | 0.80 | CYP2C19 (0.37) | CYP2C19PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8745112 | 0.77 | HPGD (0.51) | CYP2C19ALDH1A1FOLH1 | |
| SCHEMBL8433057 | 0.77 | CHRNB2 (0.34) | CYP2C19TDP1ALDH1A1 | |
| SCHEMBL8745118 | 0.77 | SMN1; SMN2 (0.44) | NPC1TDP1ALDH1A1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466220-B1 | Carboxy containing monomers and polymers and latices prepared from same | JOHNSON & JOHNSON CLIN DIAG (US) | 1997-01-29 | — | — | EP | claimed |
| EP-0462644-B1 | Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use | JOHNSON & JOHNSON CLIN DIAG (US) | 1995-10-18 | — | — | EP | claimed |
| US-5278267-A | Water insoluble vinyl aromatic polymer | EASTMAN KODAK COMPANY (US) | 1994-01-11 | — | — | US | claimed |
| US-5210289-A | Homo or coploymers for medical diagnosis | EASTMAN KODAK COMPANY (US) | 1993-05-11 | — | — | US | claimed |
| US-5155166-A | Diagnostic kits for detecting antibodies or antigens; reacting active amine- or sulfhydryl-containing compound with quaternized carboxylic polymers | EASTMAN KODAK COMPANY (US) | 1992-10-13 | — | — | US | claimed |
| US-5149737-A | Carboxy group extended from polymer surface allows easier attachment of biological substances | EASTMAN KODAK COMPANY (US) | 1992-09-22 | — | — | US | claimed |
| US-5147777-A | Analysis, diagnosis | EASTMAN KODAK COMPANY (US) | 1992-09-15 | — | — | US | claimed |
| EP-0466220-A2 | Carboxy containing monomers and polymers and latices prepared from same | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-01-15 | — | — | EP | claimed |
| EP-0462670-A1 | Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to caboxylated particles & a kit containing same | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1991-12-27 | — | — | EP | claimed |
| EP-0462644-A1 | Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1991-12-27 | — | — | EP | claimed |
| US-5888723-A | SENSITIVE HYBRIDIZATION ASSAY USING NUCLEIC ACID REAGENT COMPOSED OF OLIGONUCLEOTIDES COVALENTLY ATTACHED TO POLYMER PARTICLES WHICH ARE ADHERED TO SUPPORT USING WATER INSOLUBLE ADHESIVE; LOW BACKGROUND | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1999-03-30 | — | — | US | disclosed |
| EP-0466220-B1 | Carboxy containing monomers and polymers and latices prepared from same | JOHNSON & JOHNSON CLIN DIAG (US) | 1997-01-29 | — | — | EP | disclosed |
| EP-0462670-B1 | Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to caboxylated particles & a kit containing same | JOHNSON & JOHNSON CLIN DIAG (US) | 1996-08-21 | — | — | EP | disclosed |
| EP-0530357-B1 | ELEMENT AND METHOD FOR NUCLEIC ACID AMPLIFICATION AND DETECTION USING ADHERED PROBES | JOHNSON & JOHNSON CLIN DIAG (US) | 1995-11-15 | — | — | EP | disclosed |
| EP-0468585-B1 | Biologically active reagent, analytical element and methods for use of the reagent | JOHNSON & JOHNSON CLIN DIAG (US) | 1995-11-08 | — | — | EP | disclosed |
| US-5147777-A | Analysis, diagnosis | EASTMAN KODAK COMPANY (US) | 1992-09-15 | — | — | US | disclosed |
| EP-0468585-A2 | Biologically active reagent, analytical element and methods for use of the reagent | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-01-29 | — | — | EP | disclosed |
| EP-0466220-A2 | Carboxy containing monomers and polymers and latices prepared from same | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-01-15 | — | — | EP | disclosed |
| EP-0462670-A1 | Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to caboxylated particles & a kit containing same | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1991-12-27 | — | — | EP | disclosed |
| EP-0462644-A1 | Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1991-12-27 | — | — | EP | disclosed |