Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | FNTA | P49354 | 3/20 | 0.45 |
| ▸ | FNTB | P49356 | 3/20 | 0.45 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7839733 | 0.86 | FNTA (0.55) | GAALMNAPOLBALDH1A1MAPT | |
| SCHEMBL7856913 | 0.86 | FNTA (0.61) | GAALMNAPOLBALDH1A1MAPT | |
| SCHEMBL8438533 | 0.85 | FNTA (0.38) | GAALMNAPOLBALDH1A1FNTA | |
| SCHEMBL7839572 | 0.82 | FNTA (0.55) | GAALMNAPOLBALDH1A1MAPT | |
| SCHEMBL7838097 | 0.79 | FNTA (0.55) | GAALMNAPOLBALDH1A1MAPT | |
| SCHEMBL7839865 | 0.78 | FNTA (0.53) | GAALMNAPOLBALDH1A1MAPT | |
| SCHEMBL446699 | 0.77 | FNTA (0.53) | GAALMNAPOLBMAPTFNTA | |
| SCHEMBL7829812 | 0.76 | FNTA (0.52) | GAALMNAPOLBALDH1A1MAPT | |
| SCHEMBL7839131 | 0.76 | FNTA (0.51) | GAALMNAPOLBALDH1A1FNTA | |
| SCHEMBL7839160 | 0.74 | NPSR1 (0.53) | GAALMNAPOLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891889-A | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1999-04-06 | — | — | US | disclosed |