Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 4/20 | 0.38 |
| ▸ | FNTB | P49356 | 4/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7841845 | 0.87 | FNTA (0.51) | FNTAFNTBPGGT1BALOX5APLMNA | |
| SCHEMBL8436946 | 0.85 | GAA (0.48) | FNTAFNTBPGGT1BLMNAGAA | |
| SCHEMBL7839733 | 0.80 | FNTA (0.55) | FNTAFNTBPGGT1BLMNAGAA | |
| SCHEMBL7839728 | 0.74 | FNTA (0.51) | FNTAFNTBPGGT1BLMNAGAA | |
| SCHEMBL7837837 | 0.73 | FNTA (0.50) | FNTAFNTBPGGT1BLMNAGAA | |
| SCHEMBL8438537 | 0.72 | CYP19A1 (0.39) | FNTAFNTBPGGT1BLMNAGAA | |
| SCHEMBL7839572 | 0.71 | FNTA (0.55) | FNTAFNTBPGGT1BLMNAGAA | |
| SCHEMBL7829812 | 0.70 | FNTA (0.52) | FNTAFNTBPGGT1BLMNAGAA | |
| SCHEMBL7840054 | 0.69 | FNTA (0.49) | FNTAFNTBPGGT1BLMNAGAA | |
| SCHEMBL7839131 | 0.68 | FNTA (0.51) | FNTAFNTBPGGT1BLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891889-A | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1999-04-06 | — | — | US | disclosed |