Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octane SCHEMBL3976334 | 0.96 | CYP3A4 (0.49) | PRSS1PRSS2PRSS3CYP3A4TSHR | |
| SCHEMBL25429197 | 0.93 | LMNA (0.47) | PRSS1PRSS2PRSS3LMNAZDHHC7 | |
| SCHEMBL2711461 | 0.93 | CYP3A4 (0.52) | PRSS1PRSS2PRSS3CYP3A4TSHR | |
| SCHEMBL25428043 | 0.93 | LMNA (0.47) | PRSS1PRSS2PRSS3LMNAZDHHC7 | |
| SCHEMBL30330949 | 0.93 | LMNA (0.47) | PRSS1PRSS2PRSS3LMNAZDHHC7 | |
| SCHEMBL28533413 | 0.91 | CYP3A4 (0.50) | PRSS1PRSS2PRSS3CYP3A4TSHR | |
| SCHEMBL23535097 | 0.91 | CYP3A4 (0.50) | PRSS1PRSS2PRSS3CYP3A4TSHR | |
| SCHEMBL28532182 | 0.91 | LMNA (0.45) | PRSS1PRSS2PRSS3CYP3A4TSHR | |
| SCHEMBL28210169 | 0.91 | CYP3A4 (0.50) | PRSS1PRSS2PRSS3CYP3A4TSHR | |
| SCHEMBL28413577 | 0.91 | CYP3A4 (0.50) | PRSS1PRSS2PRSS3CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922654-A | TWO OR MORE ORGANOMETALLIC COMPOUNDS WHERE THE METAL IS A TRANSITION METAL OR SEMIMETAL, OR ZINC; FOR EXAMPLE, ZINC DIALKYLDITHIOPHOSPHATE, OR NICKEL DIALKYLDITHIOCARBAMATE; HIGHER LOAD BEARING PROPERTIES, HIGH TEMPERATURE PERFORMANCE | NSK LTD. (JP) | 1999-07-13 | — | — | US | disclosed |