Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8437140 | 0.96 | PRSS1 (0.48) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| SCHEMBL2711461 | 0.96 | CYP3A4 (0.52) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| SCHEMBL23535097 | 0.95 | CYP3A4 (0.50) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| SCHEMBL28533413 | 0.95 | CYP3A4 (0.50) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| SCHEMBL28210169 | 0.95 | CYP3A4 (0.50) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| SCHEMBL28413577 | 0.95 | CYP3A4 (0.50) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| SCHEMBL28532182 | 0.91 | LMNA (0.45) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| SCHEMBL29027154 | 0.89 | MMP9 (0.42) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| SCHEMBL25429197 | 0.89 | LMNA (0.47) | PRSS1PRSS2PRSS3CA2ZDHHC7 | |
| SCHEMBL30330949 | 0.89 | LMNA (0.47) | PRSS1PRSS2PRSS3CA2ZDHHC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1840194-B1 | Gear fluids | AFTON CHEMICAL CORP (US) | 2009-05-13 | — | — | EP | disclosed |
| US-7410935-B2 | Gear fluids | AFTON CHEMICAL CORPORATION (US) | 2008-08-12 | — | — | US | disclosed |
| EP-1840194-A1 | Gear fluids | Afton Chemical Corporation (US) | 2007-10-03 | — | — | EP | disclosed |
| US-20070225182-A1 | Gear fluids | AFTON CHEMICAL CORPORATION | 2007-09-27 | — | — | US | disclosed |
| EP-1785475-A1 | A gear additive composition | Afton Chemical Corporation (US) | 2007-05-16 | — | — | EP | disclosed |
| US-20070105729-A1 | Gear additive composition | AFTON CHEMICAL CORPORATION | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225182-A1 | Gear fluids | PHOSPHO1, F12, PIK3CA | CYP3A4 4255/4885TSHR 2476/4885TDP1 1510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.