Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MTHFD1 | P11586 | 2/20 | 0.47 |
| ▸ | MTHFD2 | P13995 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8437125 | 0.99 | MEN1 (0.52) | MEN1KMT2AMTHFD1MTHFD2POLB | |
| SCHEMBL27464735 | 0.93 | ALDH1A1 (0.44) | MEN1KMT2AMTHFD1MTHFD2ALDH1A1 | |
| SCHEMBL8439848 | 0.92 | ALDH1A1 (0.43) | MEN1KMT2AMTHFD1MTHFD2POLB | |
| SCHEMBL8438978 | 0.92 | MEN1 (0.53) | MEN1KMT2AMTHFD1MTHFD2POLB | |
| Hydrochloric Acid SCHEMBL8804440 | 0.91 | ALDH1A1 (0.43) | MEN1KMT2AMTHFD1MTHFD2POLB | |
| Hydrochloric Acid SCHEMBL8437835 | 0.91 | MEN1 (0.52) | MEN1KMT2AMTHFD1MTHFD2POLB | |
| Hydrochloric Acid SCHEMBL8439685 | 0.91 | ALDH1A1 (0.43) | MEN1KMT2AMTHFD1MTHFD2POLB | |
| SCHEMBL8439218 | 0.90 | ALDH1A1 (0.42) | MEN1KMT2AMTHFD1MTHFD2ALDH1A1 | |
| SCHEMBL8435271 | 0.90 | HPGD (0.46) | MEN1KMT2AMTHFD1MTHFD2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8437544 | 0.89 | HPGD (0.46) | MEN1KMT2AMTHFD1MTHFD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998433-A | THERAPY FOR HYPERLIPIDEMIA; ATHEROSCLEROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-12-07 | — | — | US | disclosed |
| EP-0785939-A1 | SUBSTITUTED HETEROBICYCLIC ALKYL AMINES AND THEIR USE AS SQUALENE OXIDE CYCLASE INHIBITORS | Takeda Chemical Industries, Ltd. (JP) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011201-A1 | SUBSTITUTED HETEROBICYCLIC ALKYL AMINES AND THEIR USE AS SQUALENE OXIDE CYCLASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-04-18 | — | — | WO | disclosed |