Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8435479 | 0.82 | CYP3A4 (0.40) | LMNAKMT2ATDP1CHRNB2CHRNA4 | |
| SCHEMBL23579325 | 0.82 | CHRNB1 (0.57) | CHRNB2CHRNA4CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL92404 | 0.82 | NR4A1 (0.50) | POLBLMNACHRNB2CHRNA4CHRNA7 | |
| SCHEMBL8520682 | 0.82 | POLB (0.48) | POLBGRIN2B | |
| SCHEMBL777767 | 0.80 | CHRNA7 (0.59) | CHRNA7 | |
| SCHEMBL31722127 | 0.79 | POLB (0.55) | POLB | |
| SCHEMBL26714275 | 0.79 | POLB (0.55) | POLB | |
| SCHEMBL9639986 | 0.78 | POLB (0.54) | POLB | |
| SCHEMBL14254474 | 0.78 | POLB (0.48) | POLBLMNAKMT2ATDP1CHRNB2 | |
| SCHEMBL91574 | 0.78 | POLB (0.48) | POLBLMNAKMT2ATDP1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948793-A | 3-pyridyloxymethyl heterocyclic ether compounds useful in controlling neurotransmitter release | ABBOTT LABORATORIES (US) | 1999-09-07 | — | — | US | disclosed |