Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9126535 | 1.00 | PTGS1 (0.39) | PTGS1ESR1PDE4AABCC2CACNA1C | |
| SCHEMBL8576696 | 0.90 | PTGS1 (0.42) | PTGS1ESR1PDE4AABCC2CACNA1C | |
| SCHEMBL9836778 | 0.90 | PTGS1 (0.42) | PTGS1ESR1PDE4AABCC2CACNA1C | |
| SCHEMBL9128902 | 0.90 | PTGS1 (0.42) | PTGS1ESR1PDE4AABCC2CACNA1C | |
| SCHEMBL9428011 | 0.80 | CACNA1C (0.40) | PTGS1ESR1PDE4AABCC2CACNA1C | |
| SCHEMBL9696440 | 0.80 | ESR1 (0.43) | PTGS1ESR1PDE4AABCC2CACNA1C | |
| SCHEMBL8975950 | 0.76 | ESR1 (0.42) | PTGS1ESR1PDE4AABCC2CACNA1C | |
| SCHEMBL23635214 | 0.75 | CACNA1C (0.39) | PTGS1ESR1PDE4AABCC2CACNA1C | |
| SCHEMBL23635215 | 0.74 | CACNA1C (0.39) | PTGS1ESR1PDE4AABCC2CACNA1C | |
| SCHEMBL23635266 | 0.74 | CACNA1C (0.39) | PTGS1ESR1PDE4AABCC2CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |