Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9128902 | 1.00 | PTGS1 (0.42) | PTGS1ESR1PDE4AABCC2CACNA1C | |
| SCHEMBL8576696 | 1.00 | PTGS1 (0.42) | PTGS1ESR1PDE4AABCC2CACNA1C | |
| SCHEMBL9126535 | 0.90 | PTGS1 (0.39) | PTGS1ESR1PDE4AABCC2CACNA1C | |
| SCHEMBL8437702 | 0.90 | PTGS1 (0.39) | PTGS1ESR1PDE4AABCC2CACNA1C | |
| SCHEMBL8975950 | 0.83 | ESR1 (0.42) | PTGS1ESR1PDE4AABCC2CACNA1C | |
| SCHEMBL9428011 | 0.83 | CACNA1C (0.40) | PTGS1ESR1PDE4AABCC2CACNA1C | |
| SCHEMBL8976102 | 0.82 | ELANE (0.32) | PTGS1ESR1PDE4AABCC2ELANE | |
| SCHEMBL8039606 | 0.82 | ELANE (0.32) | PTGS1ESR1PDE4AABCC2ELANE | |
| SCHEMBL8039652 | 0.80 | ESR1 (0.40) | PTGS1ESR1PDE4AABCC2CACNA1C | |
| SCHEMBL8694071 | 0.80 | ESR1 (0.40) | PTGS1ESR1PDE4AABCC2CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0202048-B1 | CARBAPENEM DERIVATIVES, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANKYO COMPANY LIMITED (JP) | 1991-10-30 | — | — | EP | disclosed |
| US-4771046-A | ANTIBIOTICS | SANKYO COMPANY, LIMITED (JP) | 1988-09-13 | — | — | US | disclosed |
| EP-0202048-A1 | Carbapenem derivatives, their preparation, and pharmaceutical compositions containing them | SANKYO COMPANY LIMITED (JP) | 1986-11-20 | — | — | EP | disclosed |