Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL27878955 | 0.95 | HSD17B10 (0.48) | CYP3A4TDP1ALDH1A1TP53HSD17B10 | |
| SCHEMBL21373 | 0.95 | TDP1 (0.48) | CYP3A4TDP1ALDH1A1TP53HSD17B10 | |
| SCHEMBL5983370 | 0.95 | TDP1 (0.48) | CYP3A4TDP1ALDH1A1TP53HSD17B10 | |
| SCHEMBL30272720 | 0.95 | TDP1 (0.48) | CYP3A4TDP1ALDH1A1TP53HSD17B10 | |
| Hypochlorous Acid SCHEMBL3965623 | 0.93 | CYP3A4 (0.42) | CYP3A4TDP1ALDH1A1TP53HSD17B10 | |
| Hydrochloric Acid SCHEMBL992776 | 0.93 | CYP3A4 (0.46) | CYP3A4TDP1ALDH1A1TP53HSD17B10 | |
| Water SCHEMBL7066183 | 0.93 | TDP1 (0.46) | CYP3A4TDP1ALDH1A1TP53HSD17B10 | |
| Hydrochloric Acid SCHEMBL134929 | 0.93 | CYP3A4 (0.46) | CYP3A4TDP1ALDH1A1TP53HSD17B10 | |
| SCHEMBL3507048 | 0.93 | TDP1 (0.46) | CYP3A4TDP1ALDH1A1TP53HSD17B10 | |
| Hydrochloric Acid SCHEMBL999548 | 0.93 | CYP3A4 (0.46) | CYP3A4TDP1ALDH1A1TP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017080989-A1 | (R)-FLURIPROFEN FOR THE PREVENTION AND/OR TREATMENT OF DIABETES | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2017-05-18 | — | — | WO | disclosed |
| EP-1690870-B1 | MARKER PEPTIDE FOR ALZHEIMER'S DISEASE | IMMUNO BIOLOGICAL LAB CO LTD (JP) | 2012-03-28 | — | — | EP | disclosed |
| US-20110014635-A1 | MARKER PEPTIDE FOR ALZHEIMER'S DISEASE | IMMUNO-BIOLOGICAL LABORATORIES CO., LTD. (JP) | 2011-01-20 | — | — | US | disclosed |
| US-7807777-B2 | Marker peptide for alzheimer's disease | IMMUNO-BIOLOGICAL LABORATORIES CO., LTD. (JP) | 2010-10-05 | — | — | US | disclosed |
| US-20080131432-A1 | Method of treating the chemotoxic effects of chemotherapeutic drugs on brain tissue | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2008-06-05 | — | — | US | disclosed |
| US-20070111252-A1 | Marker peptide for alzheimer's disease | TOSHIHARU SUZUKI (JP) | 2007-05-17 | — | — | US | disclosed |
| US-20070065882-A1 | Acetylcholinesterase-derived peptides and uses thereof | SOREQ HERMONA | 2007-03-22 | — | — | US | disclosed |
| EP-1690870-A1 | MARKER PEPTIDE FOR ALZHEIMER'S DISEASE | Suzuki, Toshiharu (JP) | 2006-08-16 | — | — | EP | disclosed |
| US-7067486-B2 | Acetylcholinesterase-derived peptides and uses thereof | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-06-27 | — | — | US | disclosed |
| WO-2005095980-A1 | DEATH-ASSOCIATED PROTEIN KINASE (DAP-KINASE) AS A NEW MARKER FOR BREAST CANCER PROGNOSIS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2005-10-13 | — | — | WO | disclosed |
| WO-1998048014-A1 | CANCER MARKER | UNIVERSITY OF LEICESTER (GB) | 1998-10-29 | — | — | WO | disclosed |
| US-5750357-A | Method of rapid analyte detection | MICROQUEST DIAGNOSTICS, INC. (US) | 1998-05-12 | — | — | US | disclosed |
| US-5422245-A | Incubating a monoclonal antibody raised against human endothelial-type PAI obtained from dexamethasone-treated human HT1080 fibrosarcoma cells which binds to the ePAI | FONDEN TIL FREMME AF EKSPERIMENTAL CANCERFORSKNING (DK) | 1995-06-06 | — | — | US | disclosed |
| EP-0390530-B1 | Retinoblastoma gene product antibodies and uses therefor | CANJI INC (US) | 1995-05-17 | — | — | EP | disclosed |
| EP-0229126-B1 | PLASMINOGEN ACTIVATOR INHIBITOR MONOCLONAL ANTIBODIES, HYBRIDOMAS, MONOCLONAL ANTIBODY PRODUCTION AND USE OF THE ANTIBODIES FOR PURIFICATION, REMOVAL, INHIBITION OR ASSAY OF THE INHIBITORS | FONDEN TIL FREMME AF EKSPERIME (DK) | 1994-04-06 | — | — | EP | disclosed |
| EP-0585995-A1 | Pure human endothelial type plasminogen activator inhibitor (e-PAI) and production thereof | FONDEN TIL FREMME AF EKSPERIMENTEL CANCERFORSKNING (DK) | 1994-03-09 | — | — | EP | disclosed |
| US-5039611-A | Hybridoma, no cross-reaction with non-urothelial cells | UNIVERSITE LAVAL (CA) | 1991-08-13 | — | — | US | disclosed |
| EP-0390530-A1 | Retinoblastoma gene product antibodies and uses therefor | CANJI, Inc. (US) | 1990-10-03 | — | — | EP | disclosed |
| EP-0229126-A1 | PLASMINOGEN ACTIVATOR INHIBITOR MONOCLONAL ANTIBODIES, HYBRIDOMAS, MONOCLONAL ANTIBODY PRODUCTION AND USE OF THE ANTIBODIES FOR PURIFICATION, REMOVAL, INHIBITION OR ASSAY OF THE INHIBITORS. | FONDEN TIL FREMME CANCERFORSK (DK) | 1987-07-22 | — | — | EP | disclosed |
| WO-1987000549-A1 | PLASMINOGEN ACTIVATOR INHIBITOR MONOCLONAL ANTIBODIES, HYBRIDOMAS, MONOCLONAL ANTIBODY PRODUCTION AND USE OF THE ANTIBODIES FOR PURIFICATION, REMOVAL, INHIBITION OR ASSAY OF THE INHIBITORS | FONDEN TIL FREMME AF EKSPERIMENTEL CANCERFORSKNING (DK) | 1987-01-29 | — | — | WO | disclosed |