SCHEMBL21373

SCHEMBL21373

Nc1ccc(-c2ccc(N)c(N)c2N)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.48
CYP3A4 P08684 4/20 0.48
ALDH1A1 P00352 4/20 0.48
TP53 P04637 2/20 0.48
HSD17B10 Q99714 4/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
MAPT P10636 2/20 0.40
TAAR1 Q96RJ0 2/20 0.40
APP P05067 1/20 0.37
TDP2 O95551 1/20 0.35
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
KIF11 P52732 1/20 0.34
PRKCZ Q05513 1/20 0.34
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5983370 1.00 TDP1 (0.48) TDP1CYP3A4ALDH1A1TP53HSD17B10
Hydrochloric Acid SCHEMBL992776 0.98 CYP3A4 (0.46) TDP1CYP3A4ALDH1A1TP53HSD17B10
SCHEMBL3507048 0.98 TDP1 (0.46) TDP1CYP3A4ALDH1A1TP53HSD17B10
Hydrochloric Acid SCHEMBL999548 0.98 CYP3A4 (0.46) TDP1CYP3A4ALDH1A1TP53HSD17B10
SCHEMBL4339278 0.98 TDP1 (0.46) TDP1CYP3A4ALDH1A1TP53HSD17B10
Water SCHEMBL7066183 0.98 TDP1 (0.46) TDP1CYP3A4ALDH1A1TP53HSD17B10
Hydrochloric Acid SCHEMBL134929 0.98 CYP3A4 (0.46) TDP1CYP3A4ALDH1A1TP53HSD17B10
Hydrogen Peroxide SCHEMBL843774 0.95 CYP3A4 (0.43) TDP1CYP3A4ALDH1A1TP53HSD17B10
Hydrochloric Acid SCHEMBL3504243 0.95 ALDH1A1 (0.43) TDP1CYP3A4ALDH1A1TP53HSD17B10
Hypochlorous Acid SCHEMBL3965623 0.93 CYP3A4 (0.42) TDP1CYP3A4ALDH1A1TP53HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 32866 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119986006-B Application of reagent for detecting GYSY-1 polypeptide in preparation of products for prognosis of colon cancer and evaluation of sensitivity of immunotherapy THE THIRD AFFILIATED HOSPITAL OF GUANGZHOU MEDICAL University (GUANGZHOU SEVERE MATERNAL RESCUE CENTER GUANGZHOU ROUJI HOSPITAL) (CN) 2026-05-26 CN claimed
EP-4211663-B1 A SCORING METHOD FOR AN ANTI-B7H4 ANTIBODY-DRUG CONJUGATE THERAPY MEDIMMUNE LTD (GB) 2026-02-18 EP claimed
EP-3684846-B1 PROCESS FOR PREPARING POLYBENZIMIDAZOLES UNIV WIEN TECH (AT) 2026-01-14 EP claimed
EP-4211598-B1 A SCORING METHOD FOR AN ANTI-HER2 ANTIBODY-DRUG CONJUGATE THERAPY ASTRAZENECA UK LTD (GB) 2026-01-07 EP claimed
US-20250354204-A1 AUTOMATED RNA DETECTION USING LABELED 2'-O-METHYL RNA OLIGONUCLEOTIDE PROBES AND SIGNAL AMPLIFICATION SYSTEMS VENTANA MED SYST INC (US) 2025-11-20 US claimed
US-12466894-B2 Anti-MUC16 antibodies and uses thereof MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2025-11-11 US claimed
EP-4621411-A1 METHOD FOR DETECTING SIALYLATED IGE Leti Pharma S.L. (ES) 2025-09-24 EP claimed
US-20250252572-A1 METHOD, SYSTEM, AND COMPUTER-READABLE RECORDING MEDIA FOR PROCESSING TISSUE IMAGES JelloX Biotech Inc. (TW) 2025-08-07 US claimed
CN-118491316-B High-temperature-resistant nanofiltration membrane based on rigid amine monomer, and preparation method and application thereof 浙江大学 2025-06-24 CN claimed
CN-120142648-A Small molecule immunodetection kit and small molecule immunodetection method 中国农业科学院蔬菜花卉研究所 2025-06-13 CN claimed
US-4610947-A Method and manufacturing polyimidazole and polyimidazopyrrolone relief structures SIEMENS AKTIENGESELLSCHAFT (DE) 1986-09-09 US claimed
WO-1986004610-A1 STABILIZED ENZYME SUBSTRATE SOLUTIONS TRAVENOL-GENENTECH DIAGNOSTICS (US) 1986-08-14 WO claimed
EP-0157932-A1 Process for the preparation of polyimidazole and polyimidazopyrrolone relief structures SIEMENS AKTIENGESELLSCHAFT (DE) 1985-10-16 EP claimed
EP-0157931-A1 Process for preparing precursors of polyimidazoles and polyimidazo pyrrolones SIEMENS AKTIENGESELLSCHAFT (DE) 1985-10-16 EP claimed
US-4397999-A TETRAAMINO AROMATIC COMPOUND, DICARBOXYLIC ACID, AND GLYCIDYL ACRYLATE OR METHACRYLATE SIEMENS AKTIENGESELLSCHAFT (DE) 1983-08-09 US claimed
EP-0024592-B1 POLYIMIDAZOLES AND POLYIMIDAZOPYRROLONE PRECURSORS AND THEIR PREPARATION SIEMENS AKTIENGESELLSCHAFT (DE) 1983-06-01 EP claimed
EP-0026299-B1 METHOD OF PRODUCING HEAT RESISTANT RELIEF STRUCTURES, RELIEF STRUCTURES PRODUCED THEREBY AND THEIR USE SIEMENS AKTIENGESELLSCHAFT (DE) 1983-04-20 EP claimed
US-4332882-A POLYIMIDAZOLES AND POLYIMIDAZOPYRROLONES SIEMENS AKTIENGESELLSCHAFT (DE) 1982-06-01 US claimed
EP-0026299-A1 Method of producing heat resistant relief structures, relief structures produced thereby and their use SIEMENS AKTIENGESELLSCHAFT (DE) 1981-04-08 EP claimed
EP-0024592-A1 Polyimidazoles and polyimidazopyrrolone precursors and their preparation SIEMENS AKTIENGESELLSCHAFT (DE) 1981-03-11 EP claimed