Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21373 | 1.00 | TDP1 (0.48) | TDP1CYP3A4ALDH1A1TP53HSD17B10 | |
| Hydrochloric Acid SCHEMBL992776 | 0.98 | CYP3A4 (0.46) | TDP1CYP3A4ALDH1A1TP53HSD17B10 | |
| SCHEMBL3507048 | 0.98 | TDP1 (0.46) | TDP1CYP3A4ALDH1A1TP53HSD17B10 | |
| Hydrochloric Acid SCHEMBL999548 | 0.98 | CYP3A4 (0.46) | TDP1CYP3A4ALDH1A1TP53HSD17B10 | |
| SCHEMBL4339278 | 0.98 | TDP1 (0.46) | TDP1CYP3A4ALDH1A1TP53HSD17B10 | |
| Water SCHEMBL7066183 | 0.98 | TDP1 (0.46) | TDP1CYP3A4ALDH1A1TP53HSD17B10 | |
| Hydrochloric Acid SCHEMBL134929 | 0.98 | CYP3A4 (0.46) | TDP1CYP3A4ALDH1A1TP53HSD17B10 | |
| Hydrogen Peroxide SCHEMBL843774 | 0.95 | CYP3A4 (0.43) | TDP1CYP3A4ALDH1A1TP53HSD17B10 | |
| Hydrochloric Acid SCHEMBL3504243 | 0.95 | ALDH1A1 (0.43) | TDP1CYP3A4ALDH1A1TP53HSD17B10 | |
| Hypochlorous Acid SCHEMBL3965623 | 0.93 | CYP3A4 (0.42) | TDP1CYP3A4ALDH1A1TP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108283722-B | Application of SPECC1L in preparation of medicines for treating liver cancer and/or preventing liver cancer recurrence after operation | 中南大学湘雅医院 | 2019-11-12 | — | — | CN | disclosed |
| CN-108624590-A | It is a kind of inhibit DDR2 expression siRNA and its application | 西安医学院 | 2018-10-09 | — | — | CN | disclosed |
| CN-108283722-A | Application of SPECC 1L in preparation of medicines for treating liver cancer and/or preventing liver cancer recurrence after operation | 中南大学湘雅医院 | 2018-07-17 | — | — | CN | disclosed |
| CN-103613669-B | Polypeptide for inhibiting cell proliferation and inducing apoptosis, preparation method and application thereof | 华中科技大学同济医学院附属同济医院 | 2016-08-17 | — | — | CN | disclosed |
| CN-104873556-A | Application of composition of astragalus polysaccharides and panax notoginseng saponins in preparing medicines for treating diabetic nephropathies | UNIV HUNAN CHINESE MEDICINE | 2015-09-02 | — | — | CN | disclosed |
| CN-103613669-A | Polypeptide for inhibiting cell proliferation and inducing apoptosis, preparation method and application thereof | AFFILIATED TONGJI HOSPITAL OF TONGJI MEDICAL COLLEGE OF HUAZHONG UNIV SCI & TECH | 2014-03-05 | — | — | CN | disclosed |
| EP-1642131-A1 | STANDARD | Dako Denmark A/S (DK) | 2006-04-05 | — | — | EP | disclosed |
| WO-2005003773-A1 | STANDARD | DAKOCYTOMATION DENMARK A/S (DK) | 2005-01-13 | — | — | WO | disclosed |