Hydrochloric Acid

Hydrochloric Acid

SCHEMBL8437786

[Cl-].[Cl-].c1ccc([S+](c2ccccc2)c2ccc(Sc3ccc([S+](c4ccccc4)c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.43
ALDH1A1 P00352 1/20 0.43
MAOA P21397 3/20 0.41
MAOB P27338 3/20 0.41
NR1H2 P55055 1/20 0.36
DDAH1 O94760 1/20 0.36
NOS1 P29475 1/20 0.36
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
SLC6A4 P31645 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MGLL Q99685 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CHRNA7 P36544 1/20 0.33
PTGIR P43119 1/20 0.33
CTSK P43235 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7612105 0.98 HPGD (0.47) HPGDALDH1A1MAOAMAOBNR1H2
SCHEMBL92199 0.97 HPGD (0.45) HPGDALDH1A1MAOAMAOBNR1H2
Iodide SCHEMBL8622120 0.95 HPGD (0.43) HPGDALDH1A1MAOAMAOBNR1H2
SCHEMBL31591283 0.95 HPGD (0.48) HPGDALDH1A1MAOAMAOBNR1H2
SCHEMBL92105 0.95 HPGD (0.48) HPGDALDH1A1MAOAMAOBNR1H2
Iodide SCHEMBL7997284 0.93 HPGD (0.47) HPGDALDH1A1MAOAMAOBNR1H2
Bromide SCHEMBL4678003 0.93 HPGD (0.47) HPGDALDH1A1MAOAMAOBNR1H2
SCHEMBL29715760 0.92 HPGD (0.50) HPGDALDH1A1MAOAMAOBNR1H2
SCHEMBL30782728 0.89 ALDH1A1 (0.39) HPGDALDH1A1MAOAMAOBCYP3A4
SCHEMBL29961986 0.89 HPGD (0.39) HPGDALDH1A1MAOAMAOBNR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4247473-A Method for producing bis-[4-(diphenylsulfonio)pheny] sulfide bis-M.X6 photoinitiator AMERICAN CAN COMPANY (US) 1981-01-27 US claimed
US-4197174-A Method for producing bis-[4-(diphenylsulfonio) phenyl] sulfide bis-MX6 AMERICAN CAN COMPANY (US) 1980-04-08 US claimed
EP-0584678-B1 Fluoroelastomer composition with organo-onium compounds DYNEON LLC (US) 1999-12-29 EP disclosed
EP-0710254-A1 CATALYSTS AND INITIATORS FOR POLYMERIZATION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-05-08 EP disclosed
US-5514728-A SALT OF A BORON ANION AND AN ONIUM CATION, CATIONIC OR FREE-RADICAL ADDITION MONOMERS, OR STEP-GROWTH POLYMERIZABLE MONOMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-05-07 US disclosed
WO-1995003338-A1 CATALYSTS AND INITIATORS FOR POLYMERIZATION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-02-02 WO disclosed
EP-0584678-A1 Fluoroelastomer composition with organo-onium compounds MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-03-02 EP disclosed
US-5262490-A Sulfonium, phosphonium and ammonium accelerators MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-11-16 US disclosed
US-4678473-A Arlysulfonium cellulosic fibers substantive to many dye classes THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1987-07-07 US disclosed
US-4247473-A Method for producing bis-[4-(diphenylsulfonio)pheny] sulfide bis-M.X6 photoinitiator AMERICAN CAN COMPANY (US) 1981-01-27 US disclosed
US-4247473-A Method for producing bis-[4-(diphenylsulfonio)pheny] sulfide bis-M.X6 photoinitiator AMERICAN CAN COMPANY (US) 1981-01-27 US disclosed
US-4247472-A Method for producing bis-[4-(diphenylsulfonic)phenyl]sulfide bis-MF6 photoinitiator AMERICAN CAN COMPANY (US) 1981-01-27 US disclosed
US-4201640-A Method for producing bis-[4-(diphenylsulfonio)phenyl] sulfide bis-M.X6 AMERICAN CAN COMPANY (US) 1980-05-06 US disclosed
US-4197174-A Method for producing bis-[4-(diphenylsulfonio) phenyl] sulfide bis-MX6 AMERICAN CAN COMPANY (US) 1980-04-08 US disclosed
US-4197174-A Method for producing bis-[4-(diphenylsulfonio) phenyl] sulfide bis-MX6 AMERICAN CAN COMPANY (US) 1980-04-08 US disclosed