Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 8/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5242224 | 0.77 | ESR1 (0.47) | ESR1ESR2 | |
| SCHEMBL15211424 | 0.74 | ESR1 (0.45) | ESR1ESR2KDM4EGAAMAPT | |
| SCHEMBL22868119 | 0.69 | HSD17B2 (0.76) | HSD17B1HSD17B2KDM4EALDH1A1HPGD | |
| SCHEMBL8289975 | 0.69 | ESR1 (0.39) | ESR1ESR2HSD17B3 | |
| SCHEMBL7942065 | 0.69 | MAPT (0.40) | ESR1ESR2DYRK1AMAPTDYRK1B | |
| SCHEMBL1616936 | 0.68 | ESR1 (0.51) | ESR1ESR2GAA | |
| SCHEMBL7405156 | 0.67 | MAPT (0.45) | HSD17B1ESR1DYRK1AALDH1A1NPC1 | |
| SCHEMBL24683228 | 0.66 | MEN1 (0.61) | KDM4EALDH1A1HPGDNPC1LMNA | |
| SCHEMBL30701686 | 0.66 | MEN1 (0.61) | KDM4EALDH1A1HPGDNPC1LMNA | |
| SCHEMBL16561524 | 0.66 | NPC1 (0.42) | ESR1ESR2ALDH1A1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5969146-A | MONOAMINE OXIDASE INHIBITORS | SYNTHELABO (FR) | 1999-10-19 | — | — | US | disclosed |