SCHEMBL8438378

SCHEMBL8438378

CCC/C=C/c1cccc(CCc2ccc(CCCC)cc2)c1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.44
MEF2D Q14814 1/20 0.44
CYP4F2 P78329 1/20 0.41
CYP4A11 Q02928 1/20 0.41
TNNC1 P63316 1/20 0.39
LPL P06858 2/20 0.39
LIPG Q9Y5X9 2/20 0.39
SKP2 Q13309 1/20 0.38
PPARA Q07869 2/20 0.38
GPR84 Q9NQS5 1/20 0.38
XIAP P98170 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8435583 0.95 LPL (0.44) HDAC4MEF2DCYP4F2CYP4A11TNNC1
SCHEMBL8438462 0.94 LPL (0.46) TNNC1LPLLIPGPPARA
SCHEMBL8434921 0.94 LPL (0.46) TNNC1LPLLIPGPPARA
SCHEMBL8433406 0.94 LPL (0.46) TNNC1LPLLIPGPPARA
SCHEMBL8437078 0.94 LPL (0.46) TNNC1LPLLIPGPPARA
SCHEMBL8438375 0.94 LPL (0.46) TNNC1LPLLIPGPPARA
SCHEMBL8436279 0.91 CYP4F2 (0.43) HDAC4MEF2DCYP4F2CYP4A11TNNC1
SCHEMBL8437053 0.89 CYP4F2 (0.42) HDAC4MEF2DCYP4F2CYP4A11TNNC1
SCHEMBL7906722 0.89 HDAC4 (0.47) HDAC4MEF2DCYP4F2CYP4A11TNNC1
SCHEMBL8437030 0.88 PPARA (0.50) TNNC1LPLLIPGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5866035-A LARGE BIREFRINGENCE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-02 US disclosed