SCHEMBL8435583

SCHEMBL8435583

CCC/C=C/c1cccc(CCc2ccc(CCCCC)cc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPL P06858 2/20 0.44
LIPG Q9Y5X9 2/20 0.44
PPARA Q07869 2/20 0.42
TNNC1 P63316 1/20 0.41
HDAC4 P56524 1/20 0.41
MEF2D Q14814 1/20 0.41
GPR3 P46089 1/20 0.40
ESR1 P03372 2/20 0.40
ADRA2A P08913 2/20 0.40
ADORA3 P0DMS8 2/20 0.40
TACR2 P21452 2/20 0.40
SLC6A2 P23975 2/20 0.40
SLC6A4 P31645 2/20 0.40
SLC6A3 Q01959 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
SHBG P04278 1/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8438375 0.99 LPL (0.46) LPLLIPGPPARATNNC1GPR3
SCHEMBL8434921 0.99 LPL (0.46) LPLLIPGPPARATNNC1GPR3
SCHEMBL8438462 0.99 LPL (0.46) LPLLIPGPPARATNNC1GPR3
SCHEMBL8433406 0.99 LPL (0.46) LPLLIPGPPARATNNC1GPR3
SCHEMBL8437078 0.99 LPL (0.46) LPLLIPGPPARATNNC1GPR3
SCHEMBL8438378 0.95 HDAC4 (0.44) LPLLIPGPPARATNNC1HDAC4
SCHEMBL8437030 0.93 PPARA (0.50) LPLLIPGPPARATNNC1ESR1
SCHEMBL8436279 0.89 CYP4F2 (0.43) PPARATNNC1HDAC4MEF2DKDM4E
SCHEMBL28801237 0.89 PPARA (0.51) LPLLIPGPPARATNNC1HDAC4
SCHEMBL8436465 0.88 TNNC1 (0.47) LPLLIPGPPARATNNC1HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5866035-A LARGE BIREFRINGENCE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-02 US disclosed