Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 8/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6714666 | 0.83 | MAPT (0.53) | SMN1; SMN2CYP2C9ALDH1A1 | |
| SCHEMBL242050 | 0.83 | MAPT (0.59) | SLC18A3SMN1; SMN2CYP2C9ALDH1A1 | |
| SCHEMBL7301802 | 0.81 | TRPV6 (0.59) | SLC18A3CYP2D6CYP2C9ALDH1A1 | |
| SCHEMBL6610401 | 0.77 | MEN1 (0.59) | SMN1; SMN2CYP2C9ALDH1A1 | |
| SCHEMBL31224897 | 0.76 | MAPT (0.55) | CYP2C9ALDH1A1 | |
| SCHEMBL7300130 | 0.75 | MAPT (0.55) | SMN1; SMN2CYP2C9ALDH1A1 | |
| SCHEMBL31224958 | 0.75 | MAPT (0.51) | SMN1; SMN2CYP2C9ALDH1A1 | |
| SCHEMBL9984902 | 0.73 | POLB (0.51) | CYP2C9ALDH1A1 | |
| SCHEMBL854301 | 0.72 | MAPT (0.56) | CYP2C9ALDH1A1 | |
| SCHEMBL2126184 | 0.72 | MAPT (0.56) | CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5876694-A | NON-INVASIVELY MAPPING CHOLINERGIC INNERVATION IN A LIVING BRAIN COMPRISES INJECTING THE BRAIN WITH A RADIOLABELLED VESAMICOL DERIVATIVE, MAGNETIC RESONANCE IMAGING | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1999-03-02 | — | — | US | disclosed |
| US-5789420-A | Azavesamicols | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1998-08-04 | — | — | US | disclosed |
| EP-0643696-A1 | AZAVESAMICOLS | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1995-03-22 | — | — | EP | disclosed |
| EP-0643696-A4 | AZAVESAMICOLS. | UNIV MINNESOTA (US) | 1995-01-20 | — | — | EP | disclosed |
| US-5338852-A | Azavesamicols | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1994-08-16 | — | — | US | disclosed |
| WO-1993024457-A1 | AZAVESAMICOLS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1993-12-09 | — | — | WO | disclosed |