Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | NT5E | P21589 | 1/20 | 0.49 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.49 |
| ▸ | KRAS | P01116 | 2/20 | 0.48 |
| ▸ | HINT1 | P49773 | 3/20 | 0.48 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.45 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.45 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.44 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.44 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441409 | 0.92 | TGM2 (0.48) | TGM2NT5EFUT5KRASHINT1 | |
| SCHEMBL8441065 | 0.92 | TGM2 (0.48) | TGM2NT5EFUT5KRASHINT1 | |
| SCHEMBL8439151 | 0.92 | TGM2 (0.48) | TGM2NT5EFUT5KRASHINT1 | |
| SCHEMBL8435618 | 0.89 | TGM2 (0.55) | TGM2NT5EFUT5KRASHINT1 | |
| SCHEMBL8441055 | 0.89 | KRAS (0.55) | TGM2NT5EFUT5KRASHINT1 | |
| SCHEMBL8441740 | 0.89 | TGM2 (0.49) | TGM2NT5EFUT5KRASHINT1 | |
| SCHEMBL8436532 | 0.88 | TGM2 (0.54) | TGM2NT5EFUT5KRASHINT1 | |
| SCHEMBL8440067 | 0.87 | FUT5 (0.53) | TGM2NT5EFUT5KRASHINT1 | |
| SCHEMBL8440912 | 0.86 | TGM2 (0.52) | TGM2NT5EFUT5KRASHINT1 | |
| SCHEMBL8440992 | 0.85 | P2RY1 (0.43) | P2RY2P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5902793-A | ADMINISTERING TO MAMMAL GAMMA-MONOALKYL- OR GAMMA-ALKENYL-NUCLEOSIDE OR DEOXYNUCLEOSIDE TRIPHOSPHATE | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 1999-05-11 | — | — | US | claimed |
| US-5639653-A | ADMINISTERING MONOALKYL- OR ALKENYL-PYROPHOSPHATE TO MAMMAL TO STIMULATE LYMPHOCYTE CELL GROWTH AND ENHANCE IMMUNE RESPONSE | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY, A DIVISION OF YESHIVA UNIVERSTIY (US) | 1997-06-17 | — | — | US | disclosed |