Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.74 |
| ▸ | ADRB1 | P08588 | 18/20 | 0.74 |
| ▸ | ADRB3 | P13945 | 17/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | TP53 | P04637 | 2/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | HTR1A | P08908 | 1/20 | 0.74 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.74 |
| ▸ | DRD2 | P14416 | 1/20 | 0.74 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.74 |
| ▸ | DRD4 | P21917 | 1/20 | 0.74 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.74 |
| ▸ | FPR3 | P25089 | 1/20 | 0.74 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.74 |
| ▸ | HTR1D | P28221 | 1/20 | 0.74 |
| ▸ | HTR1B | P28222 | 1/20 | 0.74 |
| ▸ | HTR2A | P28223 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17727765 | 0.91 | ADRB2 (0.62) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL9262566 | 0.89 | ADRB2 (0.70) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL9252012 | 0.89 | ADRB2 (0.70) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| Salmeterol SCHEMBL4767 | 0.85 | ADRB2 (1.00) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| Salmeterol SCHEMBL29393289 | 0.85 | ADRB2 (1.00) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| Salmeterol SCHEMBL4452108 | 0.85 | ADRB2 (1.00) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| Salmeterol SCHEMBL29397921 | 0.85 | ADRB2 (1.00) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| Salmeterol SCHEMBL4768 | 0.85 | ADRB2 (1.00) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL4450046 | 0.85 | ADRB2 (1.00) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL9259555 | 0.84 | ADRB2 (0.64) | ADRB2ADRB1ADRB3KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639176-A1 | BENZENEDIMETHANOL SUITABLE FOR MICRONISATION. | GLAXO GROUP LTD (GB) | 1995-02-22 | — | — | EP | claimed |
| WO-1993016031-A1 | BENZENEDIMETHANOL DERIVATIVE SUITABLE FOR MICRONISATION | GLAXO GROUP LIMITED (GB) | 1993-08-19 | — | — | WO | claimed |
| WO-1992009557-A1 | BENZENEDIMETHANOL SUITABLE FOR MICRONISATION | GLAXO CROUP LIMITED (GB) | 1992-06-11 | — | — | WO | claimed |
| CN-111067869-A | Salmeterol ticasone formula and preparation method thereof | 长沙而道新能源科技有限公司 | 2020-04-28 | — | — | CN | disclosed |
| CN-110776490-A | Synthetic method of salmeterol intermediate derivative | 刘科技 | 2020-02-11 | — | — | CN | disclosed |
| US-5871771-A | SOLUBILIZING WITH POLYLACTIDE, SOLVENT REMOVAL, JET GRINDING; TIME-RELEASE AGENTS; INHALANTS FOR ASTHMA | BOEHRINGER INGELHEIM KG (DE) | 1999-02-16 | — | — | US | disclosed |