Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23518457 | 0.92 | ALDH1A1 (0.51) | HRH4L3MBTL1ALDH1A1MAPK1MMP2 | |
| Trifluoroacetic Acid SCHEMBL7758264 | 0.88 | MEN1 (0.49) | L3MBTL1ALDH1A1MAPK1MMP2LTA4H | |
| SCHEMBL7301249 | 0.84 | ALDH1A1 (0.51) | HRH4L3MBTL1ALDH1A1MAPK1MMP2 | |
| Trifluoroacetic Acid SCHEMBL22830205 | 0.83 | ALDH1A1 (0.54) | L3MBTL1ALDH1A1MAPK1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL17335911 | 0.82 | ALDH1A1 (0.50) | HRH4L3MBTL1ALDH1A1MAPK1MMP2 | |
| Trifluoroacetic Acid SCHEMBL9335597 | 0.82 | SPHK2 (0.51) | HRH4LMNASMN1; SMN2MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL22830136 | 0.82 | ALDH1A1 (0.56) | L3MBTL1ALDH1A1MAPK1LMNAMEN1 | |
| Trifluoroacetic Acid SCHEMBL7760501 | 0.82 | SMN1; SMN2 (0.52) | L3MBTL1MMP2HTTLTA4HLMNA | |
| SCHEMBL28090584 | 0.82 | EPHX2 (0.58) | L3MBTL1ALDH1A1MAPK1HTTMEN1 | |
| Hydrochloric Acid SCHEMBL31258271 | 0.81 | ALDH1A1 (0.49) | HRH4L3MBTL1ALDH1A1MAPK1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384362-B1 | Glycinderivatives | HOFFMANN LA ROCHE (CH) | 1999-12-15 | — | — | EP | disclosed |
| US-5663297-A | OLIGOPEPTIDES | HOFFMANN-LA ROCHE INC. (US) | 1997-09-02 | — | — | US | disclosed |