Styrene

Styrene

SCHEMBL8438641

C=Cc1ccc(C(=O)NS(=O)(=O)c2ccc(OC)cc2)cc1.C=Cc1ccccc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.56
BCL2L1 Q07817 4/20 0.55
MCL1 Q07820 4/20 0.55
GFER P55789 1/20 0.53
HSD17B10 Q99714 1/20 0.53
P4HTM Q9NXG6 1/20 0.52
EGFR P00533 1/20 0.49
ERBB2 P04626 1/20 0.49
KMT2A Q03164 3/20 0.49
MEN1 O00255 2/20 0.49
LMNA P02545 1/20 0.49
FLT1 P17948 1/20 0.49
FLT4 P35916 1/20 0.49
KDR P35968 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
SNCA P37840 1/20 0.48
ALDH1A1 P00352 2/20 0.48
MAPT P10636 2/20 0.48
CYP3A4 P08684 1/20 0.48
HSPD1 P10809 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8437461 0.95 GFER (0.58) HTTBCL2L1MCL1GFERHSD17B10
Styrene SCHEMBL8441886 0.87 FLT1 (0.55) BCL2L1MCL1P4HTMEGFRKMT2A
Styrene SCHEMBL8648561 0.87 FLT1 (0.63) HTTBCL2L1MCL1P4HTMKMT2A
SCHEMBL8658489 0.86 FLT1 (0.65) HTTBCL2L1MCL1P4HTMKMT2A
SCHEMBL8520954 0.86 FLT1 (0.56) BCL2L1MCL1P4HTMEGFRKMT2A
Styrene SCHEMBL8645680 0.84 HDAC3 (0.51) BCL2L1MCL1P4HTMKMT2AMEN1
SCHEMBL7774810 0.79 HSD17B10 (0.67) HTTBCL2L1MCL1GFERHSD17B10
SCHEMBL8659346 0.79 HSD17B10 (0.67) HTTBCL2L1MCL1GFERHSD17B10
SCHEMBL795861 0.79 ALDH1A1 (0.64) HTTGFERHSD17B10P4HTMEGFR
SCHEMBL8647269 0.78 HDAC3 (0.56) KMT2AMEN1LMNAFLT1FLT4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5874194-A COPOLYMERIZED COMONOMER IS SELECTED FROM (METH)ACRYLIC ESTER, ACRYLIC ACID, ACRYLONITRILE, ALKYL ACRYLATE OR METHACRYLATE, ALKYL VINYL ETHER, VINYL ESTER, STYRENES, METHACRYLIC ACID, VINYL AMIDE, VINYL HALIDE, MALEIC ANHYDRIDE, METHACRYLAMIDE EASTMAN KODAK COMPANY (US) 1999-02-23 US disclosed