Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | DPP4 | P27487 | 5/20 | 0.53 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8440114 | 0.87 | DPP4 (0.46) | KMT2ADPP4NOX4ALDH1A1NPSR1 | |
| SCHEMBL8688625 | 0.86 | ALDH1A1 (0.60) | KMT2ADPP4NOX4ALDH1A1NPSR1 | |
| SCHEMBL8442962 | 0.85 | DPP4 (0.53) | KMT2ADPP4NOX4ALDH1A1NPSR1 | |
| SCHEMBL8441525 | 0.84 | DPP4 (0.49) | KMT2ADPP4NOX4ALDH1A1NPSR1 | |
| SCHEMBL17036598 | 0.79 | DPP4 (0.58) | KMT2ADPP4NOX4ALDH1A1RXFP1 | |
| SCHEMBL8217921 | 0.79 | DPP4 (0.54) | KMT2ADPP4NOX4ALDH1A1NPSR1 | |
| SCHEMBL6528356 | 0.77 | DPP4 (0.44) | KMT2ADPP4NOX4CYP19A1GRIN1 | |
| SCHEMBL8216924 | 0.77 | DPP4 (0.64) | KMT2ADPP4NOX4ALDH1A1NPSR1 | |
| SCHEMBL8443631 | 0.77 | ALDH1A1 (0.55) | KMT2ADPP4NOX4ALDH1A1NPSR1 | |
| SCHEMBL28406812 | 0.76 | DPP4 (0.58) | KMT2ADPP4NOX4RXFP1GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5863914-A | ADMINISTERING TO HUMAN N,N-DIMETHYLBENZENE OR N,N-DIMETHYLNAPHTHALENE-CYCLIC UREA DERIVATIVE TO TREAT A DISEASE-STATE CAUSED BY INHIBITION OF FACTOR XA | MOHAN RAJU (US) | 1999-01-26 | — | — | US | disclosed |