Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.58 |
| ▸ | DHFR | P00374 | 4/20 | 0.48 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796162 | 0.83 | EGFR (0.63) | EGFRDHFRFGFR4PDGFRBPDGFRA | |
| SCHEMBL8434815 | 0.78 | EGFR (0.53) | EGFRPDGFRBPDGFRAKIT | |
| SCHEMBL3372138 | 0.75 | EGFR (1.00) | EGFRFGFR4PDGFRBPDGFRAMEN1 | |
| Hydrochloric Acid SCHEMBL28032872 | 0.74 | EGFR (0.96) | EGFRFGFR4PDGFRBPDGFRAMEN1 | |
| SCHEMBL7804848 | 0.72 | EGFR (0.68) | EGFRDHFRFGFR4PDGFRBPDGFRA | |
| SCHEMBL28281136 | 0.72 | EGFR (0.64) | EGFRDHFRFGFR4PDE10AMEN1 | |
| SCHEMBL28158032 | 0.68 | EGFR (0.76) | EGFRFGFR4PDGFRBPDGFRAKMT2A | |
| SCHEMBL29975310 | 0.68 | EGFR (0.61) | EGFRMEN1MAPTKMT2ATDP1 | |
| Biphenyl SCHEMBL28023494 | 0.67 | EGFR (0.79) | EGFRFGFR4PDGFRBPDGFRACSF1R | |
| SCHEMBL9971309 | 0.67 | EGFR (0.51) | EGFRFGFR4ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990116-A | USE IN PREVENTION OR TREATMENT OF INFLAMMATORY AND PROLIFERATIVE SKIN DISEASES AND CANCER; COMPOUNDS SUCH AS 6-(2-(2,5-DIMETHOXYPHENYL)ETHYL)-4-ETHYL-QUINAZOLINE | NOVARTIS AG (CH) | 1999-11-23 | — | — | US | disclosed |