Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438743 | 1.00 | TK1 (0.54) | TK1TYMS | |
| SCHEMBL22984023 | 0.88 | TYMS (0.56) | TK1TYMS | |
| SCHEMBL2460809 | 0.88 | TYMS (0.56) | TK1TYMS | |
| SCHEMBL14064188 | 0.88 | TYMS (0.56) | TK1TYMS | |
| SCHEMBL22983968 | 0.88 | TYMS (0.56) | TK1TYMS | |
| SCHEMBL22983972 | 0.88 | TYMS (0.56) | TK1TYMS | |
| SCHEMBL7535874 | 0.88 | TYMS (0.56) | TK1TYMS | |
| SCHEMBL23517951 | 0.88 | TYMS (0.56) | TK1TYMS | |
| SCHEMBL2460807 | 0.88 | TYMS (0.56) | TK1TYMS | |
| SCHEMBL1775528 | 0.88 | TYMS (0.56) | TK1TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864031-A | REACTING POLYMER SUPPORTED NUCLEOSIDE (2',5'-DIDEOXY-5'-S(4,4-DIMETHOXYTRITYL) WITH AN ACID IN PRESENCE OF ARYLSULFENYL CHLORIDE, REACTING ASYMMETRICAL DISULFIDE OF NUCLEOSIDE WITH 3'-H-PHOSPHONATE SYNTHON | AMGEN INC. (US) | 1999-01-26 | — | — | US | disclosed |
| EP-0772622-A1 | 5'-DITHIO-MODIFIED OLIGONUCLEOTIDES | AMGEN INC. (US) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996004295-A1 | 5'-DITHIO-MODIFIED OLIGONUCLEOTIDES | AMGEN INC. (US) | 1996-02-15 | — | — | WO | disclosed |