Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20150135 | 0.86 | TP53 (0.39) | TAAR1TP53ESR1TSHRKCNN4 | |
| SCHEMBL3956329 | 0.77 | TAAR1 (0.39) | TAAR1TP53ESR1TSHRALDH1A1 | |
| SCHEMBL25684761 | 0.77 | TAAR1 (0.39) | TAAR1TP53ESR1TSHRALDH1A1 | |
| SCHEMBL20133786 | 0.77 | NPC1 (0.38) | TP53 | |
| SCHEMBL8959902 | 0.76 | TAAR1 (0.49) | TAAR1TP53ESR1TSHRKCNA5 | |
| SCHEMBL17045962 | 0.75 | TAAR1 (0.38) | TAAR1TP53ESR1TSHRKCNN4 | |
| SCHEMBL10473424 | 0.73 | TAAR1 (0.39) | TAAR1TP53ESR1TSHRKCNN4 | |
| SCHEMBL3954588 | 0.73 | TAAR1 (0.39) | TAAR1TP53ESR1TSHRKCNN4 | |
| SCHEMBL27814400 | 0.72 | HTR2A (0.42) | TAAR1TP53 | |
| SCHEMBL9352799 | 0.72 | TAAR1 (0.38) | TAAR1TP53ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5865857-A | COLORFASTNESS; PHOTOSTABILITY | ZENECA LIMITED (GB) | 1999-02-02 | — | — | US | disclosed |
| EP-0667887-B1 | DYES | ZENECA LTD (GB) | 1998-09-23 | — | — | EP | disclosed |
| US-5660598-A | PRODUCE LIGHTFAST BLUE TO GREEN SHADES ON SYNTHETIC TEXTILES | ZENECA LIMITED (GB) | 1997-08-26 | — | — | US | disclosed |
| EP-0667887-A1 | DYES | ZENECA LIMITED (GB) | 1995-08-23 | — | — | EP | disclosed |
| WO-1994010248-A1 | DYES | ZENECA LIMITED (GB) | 1994-05-11 | — | — | WO | disclosed |