Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13503172 | 0.88 | TAAR1 (0.46) | TAAR1ESR1TP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL25684761 | 0.83 | TAAR1 (0.39) | TAAR1ESR1TP53ALDH1A1LMNA | |
| SCHEMBL3956329 | 0.83 | TAAR1 (0.39) | TAAR1ESR1TP53ALDH1A1LMNA | |
| SCHEMBL10473424 | 0.83 | TAAR1 (0.39) | TAAR1ESR1TP53ALDH1A1LMNA | |
| SCHEMBL3954588 | 0.83 | TAAR1 (0.39) | TAAR1ESR1TP53ALDH1A1LMNA | |
| SCHEMBL2398343 | 0.82 | TAAR1 (0.47) | TAAR1ESR1TP53ALDH1A1LMNA | |
| SCHEMBL9352799 | 0.82 | TAAR1 (0.38) | TAAR1ESR1TP53SMN1; SMN2 | |
| SCHEMBL17045962 | 0.82 | TAAR1 (0.38) | TAAR1ESR1TP53ALDH1A1TSHR | |
| SCHEMBL27814400 | 0.82 | HTR2A (0.42) | TAAR1TP53LMNAMAPTCHRM2 | |
| SCHEMBL10774772 | 0.82 | SIGMAR1 (0.46) | TAAR1TP53ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018039331-A1 | NETWORK POLYMERS AND METHODS OF MAKING AND USING SAME | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2018-03-01 | — | — | WO | disclosed |
| US-7667052-B2 | Bioactive substance | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-02-23 | — | — | US | disclosed |
| US-5543569-A | Borane-N,N-dialkylaniline hydroboration agents | ALDRICH CHEMICAL COMPANY, INC. (US) | 1996-08-06 | — | — | US | disclosed |
| US-4115413-A | ACID FREE | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-19 | — | — | US | disclosed |