SCHEMBL17045962

SCHEMBL17045962

CCCN(c1ccccc1)C(C)CC.[SiH4]

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.38
TSHR P16473 2/20 0.37
ALDH1A1 P00352 1/20 0.37
GLA P06280 1/20 0.37
TP53 P04637 1/20 0.37
CRHR1 P34998 1/20 0.35
SIGMAR1 Q99720 5/20 0.35
ESR1 P03372 1/20 0.35
SLC6A9 P48067 1/20 0.33
GRIN1 Q05586 3/20 0.33
GRIN2A Q12879 3/20 0.33
GRIN2D O15399 2/20 0.33
GRIN2B Q13224 2/20 0.33
GRIN2C Q14957 2/20 0.33
KCNN4 O15554 1/20 0.33
KCNA5 P22460 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25684761 0.98 TAAR1 (0.39) TAAR1TSHRALDH1A1GLATP53
SCHEMBL3956329 0.98 TAAR1 (0.39) TAAR1TSHRALDH1A1GLATP53
SCHEMBL9352799 0.85 TAAR1 (0.38) TAAR1TP53SIGMAR1ESR1
SCHEMBL8438009 0.84 NPC1 (0.45) SIGMAR1
SCHEMBL11721433 0.83 ALDH1A1 (0.43) TSHRALDH1A1
SCHEMBL9287358 0.83 TAAR1 (0.37) TAAR1TSHRALDH1A1GLATP53
SCHEMBL2545305 0.82 TSHR (0.41) TAAR1TSHRALDH1A1GLATP53
SCHEMBL8959902 0.82 TAAR1 (0.49) TAAR1TSHRALDH1A1GLATP53
SCHEMBL9356889 0.81 SIGMAR1 (0.37) TAAR1ALDH1A1TP53SIGMAR1ESR1
SCHEMBL8438389 0.80 NPC1 (0.39) TAAR1ALDH1A1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10294250-B2 Organoaminosilanes and methods for making same VERSUM MATERIALS US, LLC (US) 2019-05-21 US disclosed
EP-3395822-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME Versum Materials US, LLC (US) 2018-10-31 EP disclosed
US-20170204120-A1 Organoaminosilanes and Methods for Making Same VERSUM MATERIALS US, LLC (US) 2017-07-20 US disclosed
US-20150246937-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150246937-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME DDAH1, IDUA, DDT TAAR1 1537/4885TSHR 3989/4885ALDH1A1 418/4885
US-20170204120-A1 Organoaminosilanes and Methods for Making Same DDAH1, IDUA, DDT TAAR1 1537/4885TSHR 3989/4885ALDH1A1 418/4885
US-10294250-B2 Organoaminosilanes and methods for making same DDAH1, IDUA, DDT TAAR1 1537/4885TSHR 3989/4885ALDH1A1 418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.