Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7917755 | 0.89 | MEN1 (0.53) | MEN1KMT2ANR1I2THRBP2RX7 | |
| SCHEMBL5566665 | 0.80 | MEN1 (0.58) | MEN1KMT2ANR1I2THRBP2RX7 | |
| SCHEMBL7917028 | 0.75 | MEN1 (0.69) | MEN1KMT2ANR1I2NPSR1THRB | |
| SCHEMBL7922440 | 0.74 | KMT2A (0.41) | MEN1KMT2ANR1I2NPSR1THRB | |
| SCHEMBL5561613 | 0.70 | MEN1 (0.52) | MEN1KMT2ANR1I2THRBMAPT | |
| SCHEMBL6479192 | 0.70 | KMT2A (0.50) | MEN1KMT2ANR1I2P2RX7HTT | |
| SCHEMBL7472949 | 0.70 | MEN1 (0.51) | MEN1KMT2ANR1I2THRBP2RX7 | |
| SCHEMBL6701530 | 0.69 | MEN1 (0.45) | MEN1KMT2ANR1I2THRBP2RX7 | |
| SCHEMBL7919391 | 0.69 | NPSR1 (0.38) | MEN1KMT2ANPSR1MAPTHTT | |
| SCHEMBL7264062 | 0.67 | HPGD (0.49) | MEN1KMT2ANPSR1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994355-A | ANTIPROTOZOA AGENTS, PARASITICIDE; VETERINARY MEDICINE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0648760-B1 | Triazine derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-01-27 | — | — | EP | disclosed |
| EP-0648760-A2 | Triazine derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |