SCHEMBL6701530

SCHEMBL6701530

O=C(c1ccc(Cl)cc1)c1c(Cl)cc(Cl)cc1-n1ncc(=O)[nH]c1=O

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.45
NR1I2 O75469 1/20 0.45
KMT2A Q03164 1/20 0.45
P2RX7 Q99572 10/20 0.39
ALOX15 P16050 2/20 0.38
ABCB11 O95342 1/20 0.37
HTT P42858 2/20 0.35
THRA P10827 1/20 0.35
THRB P10828 1/20 0.35
TYMP P19971 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5566665 0.85 MEN1 (0.58) MEN1NR1I2KMT2AP2RX7ABCB11
SCHEMBL7917755 0.80 MEN1 (0.53) MEN1NR1I2KMT2AP2RX7THRA
SCHEMBL6479192 0.79 KMT2A (0.50) MEN1NR1I2KMT2AP2RX7ABCB11
SCHEMBL10413461 0.77 ALOX12 (0.51) MEN1NR1I2KMT2AP2RX7HTT
SCHEMBL5561613 0.77 MEN1 (0.52) MEN1NR1I2KMT2AP2RX7ABCB11
SCHEMBL7472949 0.74 MEN1 (0.51) MEN1NR1I2KMT2AP2RX7ABCB11
SCHEMBL6701534 0.72 P2RX7 (0.47) MEN1NR1I2KMT2AP2RX7ABCB11
SCHEMBL7909905 0.71 KMT2A (0.58) MEN1NR1I2KMT2AP2RX7ABCB11
SCHEMBL10414300 0.70 KMT2A (0.45) MEN1NR1I2KMT2AP2RX7ABCB11
SCHEMBL7919792 0.69 MEN1 (0.56) MEN1NR1I2KMT2AP2RX7ABCB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040167333-A1 Novel IL-5 inhibiting 6-azauracil derivatives for marking and identifying receptors and imaging organs LACRAMPE JEAN FERNAND ARMAND (FR) 2004-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040167333-A1 Novel IL-5 inhibiting 6-azauracil derivatives for marking and identifying receptors and imaging organs IL6ST, CXCR5, ALOX5 MEN1 4239/4885NR1I2 203/4885KMT2A 4336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.