Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | SCN4A | P35499 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4985324 | 0.94 | SLC2A1 (0.51) | SLC2A1ADRB2SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL9198692 | 0.86 | ADRB2 (0.52) | SLC2A1ADRB2SLC6A2SLC6A3SLC6A4 | |
| Ammonia Solution, Strong SCHEMBL386864 | 0.84 | ADRB2 (0.50) | SLC2A1ADRB2SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL9350707 | 0.83 | SLC2A1 (0.59) | SLC2A1SLC6A4CA2OPRM1 | |
| SCHEMBL2769246 | 0.83 | ADRB2 (0.45) | SLC2A1ADRB2SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL8249194 | 0.83 | ADRB2 (0.45) | SLC2A1ADRB2SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL9439771 | 0.82 | SLC2A1 (0.60) | SLC2A1SLC6A4CA2OPRM1 | |
| SCHEMBL20697728 | 0.81 | SLC2A1 (0.63) | SLC2A1CA2OPRM1 | |
| SCHEMBL22129792 | 0.81 | SLC2A1 (0.58) | SLC2A1SLC6A4CA2OPRM1 | |
| SCHEMBL9043076 | 0.81 | SLC2A1 (0.63) | SLC2A1CA2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990102-A | Substituted azetidin-2-ones for treatment of atherosclerosis | SMITHKLINE BEECHAM P.L.C. (GB) | 1999-11-23 | — | — | US | disclosed |
| EP-0799200-A1 | SUBSTITUTED AZETIDIN-2-ONES FOR TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996019451-A1 | SUBSTITUTED AZETIDIN-2-ONES FOR TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1996-06-27 | — | — | WO | disclosed |