Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.35 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8443304 | 0.89 | ABCB1 (0.61) | ABCB1IDO1ABCC9KCNA5 | |
| SCHEMBL8439228 | 0.79 | ABCB1 (0.38) | ABCB1IDO1ABCC9 | |
| SCHEMBL2888730 | 0.78 | NPC1 (0.42) | ABCB1KCNE1KCNQ1KCNA5 | |
| SCHEMBL2888729 | 0.78 | NPC1 (0.42) | ABCB1KCNE1KCNQ1KCNA5 | |
| Hydrochloric Acid SCHEMBL2883774 | 0.78 | NPC1 (0.41) | ABCB1KCNE1KCNQ1KCNA5 | |
| Hydrochloric Acid SCHEMBL2883776 | 0.78 | NPC1 (0.41) | ABCB1KCNE1KCNQ1KCNA5 | |
| SCHEMBL10916183 | 0.77 | ABCB1 (0.53) | ABCB1KCNA5 | |
| SCHEMBL8443474 | 0.77 | ABCC9 (0.40) | ABCB1ABCC9 | |
| SCHEMBL8441901 | 0.76 | ABCC9 (0.37) | ABCB1IDO1ABCC9 | |
| SCHEMBL8438968 | 0.73 | ABCB1 (0.37) | ABCB1IDO1ABCC9KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919806-A | 8-AMINOPYRANO(2.3-F)BENZO-OXADIAZOLES, THIADIAZOLES AND TRIAZOLES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-06 | — | — | US | disclosed |
| EP-0693283-A1 | HEART FAILURE REMEDY | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1996-01-24 | — | — | EP | disclosed |