Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.61 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 7/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8439045 | 0.89 | ABCB1 (0.48) | ABCB1IDO1KCNA5ABCC9 | |
| SCHEMBL8439228 | 0.81 | ABCB1 (0.38) | ABCB1IDO1ABCC9 | |
| SCHEMBL7253231 | 0.80 | ABCB1 (0.68) | ABCB1IDO1KCNA5ABCC9 | |
| SCHEMBL2009405 | 0.79 | ABCB1 (0.53) | ABCB1IDO1KCNA5ABCC9 | |
| SCHEMBL2878735 | 0.79 | ABCB1 (0.53) | ABCB1IDO1KCNA5ABCC9 | |
| SCHEMBL8443474 | 0.79 | ABCC9 (0.40) | ABCB1ABCC9 | |
| SCHEMBL8441901 | 0.78 | ABCC9 (0.37) | ABCB1IDO1ABCC9 | |
| SCHEMBL2007669 | 0.77 | ABCB1 (0.48) | ABCB1IDO1KCNA5ABCC9 | |
| SCHEMBL8438968 | 0.77 | ABCB1 (0.37) | ABCB1IDO1KCNA5ABCC9 | |
| SCHEMBL2888894 | 0.77 | ABCB1 (0.48) | ABCB1IDO1KCNA5ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919806-A | 8-AMINOPYRANO(2.3-F)BENZO-OXADIAZOLES, THIADIAZOLES AND TRIAZOLES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-06 | — | — | US | disclosed |
| EP-0693283-A1 | HEART FAILURE REMEDY | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1996-01-24 | — | — | EP | disclosed |