Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 6/20 | 0.36 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8374887 | 1.00 | BCHE (0.41) | BCHEACHEFFAR1F10F2 | |
| SCHEMBL8440642 | 0.88 | BCHE (0.41) | BCHEACHEFFAR1F10F2 | |
| SCHEMBL8374494 | 0.88 | BCHE (0.41) | BCHEACHEFFAR1F10F2 | |
| Guanidine SCHEMBL8517609 | 0.82 | F10 (0.41) | BCHEACHEFFAR1F10F2 | |
| SCHEMBL8377548 | 0.79 | MAPT (0.37) | BCHEACHEFFAR1F10F2 | |
| SCHEMBL8439020 | 0.72 | FFAR1 (0.43) | BCHEACHEFFAR1F10F2 | |
| SCHEMBL8373819 | 0.72 | FFAR1 (0.43) | BCHEACHEFFAR1F10F2 | |
| SCHEMBL2565952 | 0.71 | AKR1C3 (0.53) | — | |
| SCHEMBL2565950 | 0.71 | AKR1C3 (0.53) | — | |
| SCHEMBL31283977 | 0.69 | ATM (0.52) | NPC1MAPTRAB9AALDH1A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755919-B1 | Substituted cinnamic acid guanidides, process for their preparation, their use as cardiovascualr medicament or diagnostic agent, as well as medicament containing them | HOECHST AG (DE) | 1999-11-17 | — | — | EP | claimed |