Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | SLC9A3 | P48764 | 2/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8374494 | 1.00 | BCHE (0.41) | BCHEACHEFFAR1AKR1C3SLC9A3 | |
| Guanidine SCHEMBL8517609 | 0.94 | F10 (0.41) | BCHEACHEFFAR1AKR1C3SLC9A3 | |
| SCHEMBL8439128 | 0.88 | BCHE (0.41) | BCHEACHEFFAR1F2F10 | |
| SCHEMBL8374887 | 0.88 | BCHE (0.41) | BCHEACHEFFAR1F2F10 | |
| SCHEMBL8377548 | 0.85 | MAPT (0.37) | BCHEACHEFFAR1SLC9A3TUBB1 | |
| SCHEMBL2565952 | 0.85 | AKR1C3 (0.53) | AKR1C3SLC9A3TUBB1APEX1ESR1 | |
| SCHEMBL2565950 | 0.85 | AKR1C3 (0.53) | AKR1C3SLC9A3TUBB1APEX1ESR1 | |
| SCHEMBL8373819 | 0.82 | FFAR1 (0.43) | BCHEACHEFFAR1AKR1C3F2 | |
| SCHEMBL8439020 | 0.82 | FFAR1 (0.43) | BCHEACHEFFAR1AKR1C3F2 | |
| SCHEMBL8442998 | 0.78 | FFAR1 (0.39) | BCHEACHEFFAR1F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755919-B1 | Substituted cinnamic acid guanidides, process for their preparation, their use as cardiovascualr medicament or diagnostic agent, as well as medicament containing them | HOECHST AG (DE) | 1999-11-17 | — | — | EP | claimed |