Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.53 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6209967 | 0.95 | CYP4F2 (0.53) | CYP4F2CYP4A11CDYLALDH1A1LMNA | |
| SCHEMBL28212143 | 0.85 | CYP4F2 (0.47) | CYP4F2CYP4A11ALDH1A1LMNAGAA | |
| SCHEMBL2821947 | 0.85 | CYP4F2 (0.47) | CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL14110364 | 0.84 | CYP4F2 (0.41) | CYP4F2CYP4A11MTNR1AMTNR1B | |
| SCHEMBL29059884 | 0.83 | CTSS (0.43) | CYP4F2CYP4A11ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL6987122 | 0.83 | MEN1 (0.47) | CYP4F2CYP4A11ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL16575622 | 0.83 | CYP4F2 (0.43) | CYP4F2CYP4A11ALDH1A1LMNAMTNR1A | |
| SCHEMBL30339213 | 0.82 | FOLH1 (0.51) | CYP4F2CYP4A11ALDH1A1LMNAMTNR1A | |
| SCHEMBL6802490 | 0.82 | FOLH1 (0.51) | CYP4F2CYP4A11ALDH1A1LMNAMTNR1A | |
| SCHEMBL7286194 | 0.81 | CDYL (0.56) | CYP4F2CYP4A11CDYLMTNR1AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889178-A | N-(2,2-DIPHENYLETHYL)-DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-03-30 | — | — | US | disclosed |