Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 12/20 | 0.55 |
| ▸ | DRD2 | P14416 | 4/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441075 | 0.87 | HTR1A (0.57) | HTR1ADRD2HTR2A | |
| SCHEMBL8442339 | 0.86 | HTR1A (0.54) | HTR1AALDH1A1LMNACYP3A4ALOX12 | |
| SCHEMBL8440430 | 0.85 | HTR1A (0.57) | HTR1ADRD2HTR1DALDH1A1LMNA | |
| SCHEMBL8443885 | 0.84 | HTR1A (0.41) | HTR1ADRD2 | |
| SCHEMBL8441929 | 0.83 | HTR1A (0.46) | HTR1AALDH1A1LMNACYP3A4ALOX12 | |
| SCHEMBL8440360 | 0.82 | HTR1A (0.57) | HTR1A | |
| SCHEMBL8443030 | 0.80 | HTR1A (0.57) | HTR1ADRD2HTR1DALDH1A1LMNA | |
| SCHEMBL8440322 | 0.79 | HTR1A (0.56) | HTR1A | |
| SCHEMBL8439530 | 0.75 | HTR1A (0.57) | HTR1A | |
| SCHEMBL13533188 | 0.74 | HTR1A (0.76) | HTR1AALDH1A1LMNACYP3A4ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958927-A | PSYCHOLOGICAL AND NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1999-09-28 | — | — | US | claimed |
| US-5958927-A | PSYCHOLOGICAL AND NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1999-09-28 | — | — | US | disclosed |