Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 12/20 | 0.41 |
| ▸ | PKLR | P30613 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8440360 | 0.85 | HTR1A (0.57) | HTR1ASLC6A4 | |
| SCHEMBL8439359 | 0.84 | HTR1A (0.55) | HTR1ADRD2 | |
| SCHEMBL8440322 | 0.79 | HTR1A (0.56) | HTR1ASLC6A4CTNNB1WNT3A | |
| SCHEMBL8439530 | 0.78 | HTR1A (0.57) | HTR1ASLC6A4 | |
| SCHEMBL8439326 | 0.76 | HTR1A (0.58) | HTR1ASLC6A4 | |
| SCHEMBL8440473 | 0.75 | HTR1A (0.43) | HTR1ASLC6A4P2RX7 | |
| SCHEMBL6959319 | 0.75 | HTR1A (0.69) | HTR1A | |
| SCHEMBL6959323 | 0.75 | HTR1A (0.69) | HTR1A | |
| SCHEMBL8439452 | 0.73 | HTR1A (0.56) | HTR1ASLC6A4DRD2 | |
| SCHEMBL8441075 | 0.73 | HTR1A (0.57) | HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958927-A | PSYCHOLOGICAL AND NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1999-09-28 | — | — | US | disclosed |