Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 16/20 | 0.56 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8439530 | 0.90 | HTR1A (0.57) | HTR1ASLC6A4 | |
| SCHEMBL8440360 | 0.89 | HTR1A (0.57) | HTR1ASLC6A4 | |
| SCHEMBL8443664 | 0.88 | HTR1A (0.56) | HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL8443738 | 0.85 | HTR1A (0.53) | HTR1A | |
| SCHEMBL8440860 | 0.85 | HTR1A (0.46) | HTR1AKDM1ADRD2HTR2ADRD3 | |
| SCHEMBL8440115 | 0.85 | HTR1A (0.57) | HTR1AKDM1ADRD2HTR2ADRD3 | |
| SCHEMBL8439326 | 0.78 | HTR1A (0.58) | HTR1ASLC6A4 | |
| SCHEMBL8441675 | 0.77 | HTR1A (0.59) | HTR1ASLC6A4 | |
| SCHEMBL8440473 | 0.76 | HTR1A (0.43) | HTR1ASLC6A4 | |
| SCHEMBL8443885 | 0.73 | HTR1A (0.41) | HTR1ASLC6A4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958927-A | PSYCHOLOGICAL AND NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1999-09-28 | — | — | US | disclosed |