Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 9/20 | 0.51 |
| ▸ | WNT3A | P56704 | 9/20 | 0.51 |
| ▸ | F2R | P25116 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29410857 | 0.86 | CTNNB1 (0.57) | LMNAGAACTNNB1WNT3AF2R | |
| SCHEMBL1950901 | 0.86 | CTNNB1 (0.57) | LMNAGAACTNNB1WNT3AF2R | |
| SCHEMBL6603074 | 0.86 | CTSS (0.53) | LMNAGAACTNNB1WNT3AF2R | |
| Hydrochloric Acid SCHEMBL5819908 | 0.84 | CTNNB1 (0.55) | LMNAGAACTNNB1WNT3AF2R | |
| SCHEMBL8489375 | 0.83 | LMNA (0.56) | LMNAGAACTNNB1WNT3AF2R | |
| SCHEMBL3549199 | 0.80 | LMNA (0.53) | LMNAGAACTNNB1WNT3AF2R | |
| SCHEMBL401715 | 0.80 | LMNA (0.49) | LMNAGAACTNNB1WNT3AF2R | |
| SCHEMBL31475594 | 0.79 | LMNA (0.56) | LMNAGAACTNNB1WNT3AKCNK3 | |
| SCHEMBL18662346 | 0.79 | CTNNB1 (0.62) | LMNAGAACTNNB1WNT3AF2R | |
| SCHEMBL3474396 | 0.79 | LMNA (0.56) | LMNAGAACTNNB1WNT3AKCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929510-A2 | PROCESSES FOR THE PREPARATION OF ARYL-$g(b)-DIKETONES, ARYL-PYRIMIDINE KETONES AND CROP PROTECTION INTERMEDIATES | ZENECA LIMITED (GB) | 1999-07-21 | — | — | EP | disclosed |
| US-5925795-A | Processes for the preparation of aryl-β-diketones, arylpyrimidine ketones and crop protection intermediates | ZENECA LIMITED (GB) | 1999-07-20 | — | — | US | disclosed |
| WO-1998011046-A2 | PROCESSES FOR THE PREPARATION OF ARYL-β-DIKETONES, ARYL-PYRIMIDINE KETONES AND CROP PROTECTION INTERMEDIATES | ZENECA LIMITED (GB) | 1998-03-19 | — | — | WO | disclosed |
| US-5672567-A | PRE- AND POST-EMERGENCE | ZENECA LIMITED (GB) | 1997-09-30 | — | — | US | disclosed |
| US-5670453-A | PYRAZINEARYL COMPOUND | ZENECA LIMITED (GB) | 1997-09-23 | — | — | US | disclosed |
| WO-1995029898-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1995-11-09 | — | — | WO | disclosed |