Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 4/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.42 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.42 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.42 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | RNASEL | Q05823 | 3/20 | 0.40 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.39 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.38 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8439414 | 0.99 | P2RY1 (0.41) | P2RY1ENPP1P2RX3P2RX1P2RY6 | |
| SCHEMBL8435235 | 0.99 | P2RY1 (0.41) | P2RY1ENPP1P2RX3P2RX1P2RY6 | |
| SCHEMBL8440992 | 0.92 | P2RY1 (0.43) | P2RY1ENPP1P2RX3P2RX1P2RY6 | |
| SCHEMBL8435672 | 0.90 | P2RY2 (0.44) | P2RY1P2RX3RNASELP2RX2P2RY2 | |
| SCHEMBL8441096 | 0.90 | P2RY2 (0.43) | P2RY1P2RX3RNASELP2RX2P2RY2 | |
| SCHEMBL8436367 | 0.90 | P2RY2 (0.43) | P2RY1P2RX3RNASELP2RX2P2RY2 | |
| SCHEMBL8435720 | 0.88 | RNASEL (0.41) | P2RY6RNASELP2RY2 | |
| SCHEMBL8440037 | 0.87 | RNASEL (0.41) | P2RY6RNASELP2RY2 | |
| SCHEMBL8435811 | 0.86 | P2RY1 (0.44) | P2RY1ENPP1P2RX3P2RX1P2RY6 | |
| SCHEMBL8440902 | 0.86 | P2RY1 (0.42) | P2RY1ENPP1P2RX3P2RX1P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5902793-A | ADMINISTERING TO MAMMAL GAMMA-MONOALKYL- OR GAMMA-ALKENYL-NUCLEOSIDE OR DEOXYNUCLEOSIDE TRIPHOSPHATE | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 1999-05-11 | — | — | US | claimed |
| US-5639653-A | ADMINISTERING MONOALKYL- OR ALKENYL-PYROPHOSPHATE TO MAMMAL TO STIMULATE LYMPHOCYTE CELL GROWTH AND ENHANCE IMMUNE RESPONSE | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY, A DIVISION OF YESHIVA UNIVERSTIY (US) | 1997-06-17 | — | — | US | disclosed |