SCHEMBL8435720

CC(C)=CCC/C(C)=C/CC(OP(=O)(O)OP(=O)(O)OP(=O)(O)O[C@H]1[C@@H](O)[C@H](n2ccc(=O)[nH]c2=O)O[C@@H]1C(C/C=C(\C)CCC=C(C)C)OP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@H]1O[C@@H](n2cnc3c(O)nc(O)nc32)[C@H](O)[C@@H]1O

nearest known ligand 0.41

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	RNASEL	Q05823	4/20	0.41

▸	P2RY2	P41231	12/20	0.41

▸	P2RY6	Q15077	6/20	0.40

▸	P2RY4	P51582	6/20	0.40

▸	P2RY14	Q15391	3/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8440037	0.99	RNASEL (0.41)	RNASELP2RY2P2RY6P2RY4P2RY14
SCHEMBL8439657	0.88	P2RY1 (0.42)	RNASELP2RY2P2RY6
SCHEMBL8439414	0.87	P2RY1 (0.41)	RNASELP2RY2P2RY6
SCHEMBL8435235	0.87	P2RY1 (0.41)	RNASELP2RY2P2RY6
SCHEMBL8439482	0.85	P2RY2 (0.52)	P2RY2P2RY6P2RY4P2RY14
SCHEMBL8439098	0.85	P2RY2 (0.51)	P2RY2P2RY6P2RY4P2RY14
SCHEMBL8439811	0.85	P2RY2 (0.51)	P2RY2P2RY6P2RY4P2RY14
SCHEMBL8440992	0.81	P2RY1 (0.43)	RNASELP2RY2P2RY6
SCHEMBL8435672	0.79	P2RY2 (0.44)	RNASELP2RY2
SCHEMBL8441409	0.79	TGM2 (0.48)	P2RY2P2RY6P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5902793-A	ADMINISTERING TO MAMMAL GAMMA-MONOALKYL- OR GAMMA-ALKENYL-NUCLEOSIDE OR DEOXYNUCLEOSIDE TRIPHOSPHATE	ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US)	1999-05-11	—	—	US	disclosed