SCHEMBL8439715

SCHEMBL8439715

Nc1ccc(NC(=O)c2ccc(O)cc2)cc1

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.85
TDP1 Q9NUW8 2/20 0.85
MEN1 O00255 1/20 0.85
LMNA P02545 1/20 0.85
PKM P14618 1/20 0.85
APEX1 P27695 1/20 0.85
KMT2A Q03164 1/20 0.85
PTGS1 P23219 2/20 0.67
CA12 O43570 1/20 0.65
CA1 P00915 1/20 0.65
CA2 P00918 1/20 0.65
CA9 Q16790 1/20 0.65
DEGS1 O15121 3/20 0.64
SNCA P37840 2/20 0.64
MAPT P10636 3/20 0.63
NQO2 P16083 2/20 0.61
RAB9A P51151 2/20 0.59
NPC1 O15118 1/20 0.59
TP53 P04637 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2587802 1.00 POLB (0.85) POLBTDP1MEN1LMNAPKM
SCHEMBL30319980 0.92 POLB (1.00) POLBTDP1MEN1LMNAPKM
SCHEMBL1353478 0.92 POLB (1.00) POLBTDP1MEN1LMNAPKM
SCHEMBL137276 0.92 POLB (1.00) POLBTDP1MEN1LMNAPKM
SCHEMBL2128727 0.92 POLB (1.00) POLBTDP1MEN1LMNAPKM
SCHEMBL9681496 0.92 POLB (1.00) POLBTDP1MEN1LMNAPKM
SCHEMBL8442129 0.90 POLB (0.96) POLBTDP1MEN1LMNAPKM
Hydrochloric Acid SCHEMBL8640632 0.90 POLB (0.96) POLBTDP1MEN1LMNAPKM
SCHEMBL900928 0.90 DEGS1 (0.75) POLBTDP1MEN1LMNAPKM
SCHEMBL8420639 0.90 DEGS1 (0.75) POLBTDP1MEN1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109305925-B Multifunctional bio-based phenol amine antioxidant, and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2022-03-08 CN disclosed
CN-109305925-A Multifunctional bio base phenol amine antioxidants, preparation method and application 中国科学院宁波材料技术与工程研究所 2019-02-05 CN disclosed
EP-0409070-B1 Mesogenic cyanite functional maleimides and thermosets thereof DOW CHEMICAL CO (US) 1999-03-03 EP disclosed
US-5399673-A Polymerizable monomers THE DOW CHEMICAL COMPANY (US) 1995-03-21 US disclosed
US-5248758-A Curable composition THE DOW CHEMICAL COMPANY (US) 1993-09-28 US disclosed
US-5248757-A Curable composition THE DOW CHEMICAL COMPANY (US) 1993-09-28 US disclosed
US-5208306-A Mesogenic alkenyl functional maleimides and thermosets thereof THE DOW CHEMICAL COMPANY (US) 1993-05-04 US disclosed
US-5159030-A Molecular orientated, curable liquid crystal THE DOW CHEMICAL COMPANY (US) 1992-10-27 US disclosed
US-5077380-A Mesogenic cyanate functional maleimides and thermosets thereof THE DOW CHEMICAL COMPANY (US) 1991-12-31 US disclosed
EP-0409070-A2 Mesogenic cyanite functional maleimides and thermosets thereof THE DOW CHEMICAL COMPANY (US) 1991-01-23 EP disclosed
US-4069206-A HYGROSCOPIC, PHOTOSENSITIVITY TEIJIN LIMITED (JA) 1978-01-17 US disclosed