SCHEMBL900928

SCHEMBL900928

O=C(Nc1ccc(O)cc1)c1ccc(C(=O)Nc2ccc(O)cc2)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DEGS1 O15121 3/20 0.75
SNCA P37840 1/20 0.75
NQO2 P16083 2/20 0.73
POLB P06746 2/20 0.67
KDM4E B2RXH2 2/20 0.67
NPC1 O15118 4/20 0.65
RAB9A P51151 4/20 0.65
MEN1 O00255 2/20 0.65
KMT2A Q03164 2/20 0.65
LMNA P02545 1/20 0.65
PKM P14618 1/20 0.65
APEX1 P27695 1/20 0.65
TDP1 Q9NUW8 1/20 0.65
TOP1 P11387 1/20 0.61
TP53 P04637 2/20 0.59
GAA P10253 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
PTPN1 P18031 1/20 0.59
ALOX15 P16050 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL899585 1.00 DEGS1 (0.75) DEGS1SNCANQO2POLBKDM4E
SCHEMBL8420639 1.00 DEGS1 (0.75) DEGS1SNCANQO2POLBKDM4E
SCHEMBL20284045 0.94 DEGS1 (0.86) DEGS1SNCANQO2POLBKDM4E
SCHEMBL8770541 0.94 DEGS1 (0.68) DEGS1SNCANQO2POLBKDM4E
SCHEMBL11688443 0.92 DEGS1 (0.83) DEGS1SNCANQO2POLBKDM4E
SCHEMBL4491689 0.90 PTPN1 (0.76) DEGS1SNCANQO2POLBNPC1
SCHEMBL11676225 0.90 MEN1 (0.77) DEGS1SNCANQO2POLBKDM4E
SCHEMBL6555948 0.90 RAB9A (0.85) DEGS1SNCANQO2POLBKDM4E
SCHEMBL10439291 0.90 TRPV1 (0.67) DEGS1SNCANQO2POLBKDM4E
SCHEMBL2461226 0.90 MAPT (0.71) DEGS1SNCANQO2POLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0379055-B1 Mesogenic advanced epoxy compounds DOW CHEMICAL CO (US) 1999-11-10 EP claimed
EP-0573573-B1 MESOGENIC GLYCIDYL AMINES DOW CHEMICAL CO (US) 1999-09-29 EP claimed
US-5602211-A CURING AGENTS THE DOW CHEMICAL COMPANY (US) 1997-02-11 US claimed
US-5412044-A Nitro group terminated mesogenic epoxy resin adducts THE DOW CHEMICAL COMPANY (US) 1995-05-02 US claimed
US-5391651-A Curable mixtures of mesogenic epoxy resins and mesogenic polyamines and cured compositions THE DOW CHEMICAL COMPANY (US) 1995-02-21 US claimed
US-5364912-A Anisotropic melts, reaction of glycidyl ester of dicarboxylic acid and diol or dicarboxylic acid THE DOW CHEMICAL COMPANY (US) 1994-11-15 US claimed
US-5342904-A Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1994-08-30 US claimed
EP-0573573-A1 MESOGENIC GLYCIDYL AMINES THE DOW CHEMICAL COMPANY (US) 1993-12-15 EP claimed
US-5270406-A Advanced epoxy resin compositions containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1993-12-14 US claimed
US-5270405-A Mesogenic epoxy compounds THE DOW CHEMICAL COMPANY (US) 1993-12-14 US claimed
US-5270404-A Curable compositions of mesogen-containing advanced epoxy resins and curing agents therefor THE DOW CHEMICAL COMPANY (US) 1993-12-14 US claimed
US-5266661-A Epoxy resins THE DOW CHEMICAL COMPANY (US) 1993-11-30 US claimed
US-5248740-A Thioepoxides, liquid crystal polymers THE DOW CHEMICAL COMPANY (US) 1993-09-28 US claimed
US-5235008-A Curable THE DOW CHEMICAL COMPANY (US) 1993-08-10 US claimed
US-5218062-A Curable mixtures of mesogenic epoxy resins and mesogenic polyamines and cured compositions THE DOW CHEMICAL COMPANY (US) 1993-06-08 US claimed
US-5182340-A Molding materials having shorter gel time with aliphatic amine curing agents THE DOW CHEMICAL COMPANY (US) 1993-01-26 US claimed
WO-1992015630-A2 MESOGENIC GLYCIDYL AMINES THE DOW CHEMICAL COMPANY (US) 1992-09-17 WO claimed
EP-0475238-A2 Mesogenic glycidyl esters THE DOW CHEMICAL COMPANY (US) 1992-03-18 EP claimed
EP-0473935-A2 Curable mixture of mesogenic epoxy resins and mesogenic polyamines and cured compositions THE DOW CHEMICAL COMPANY (US) 1992-03-11 EP claimed
EP-0379055-A2 Mesogenic advanced epoxy compounds THE DOW CHEMICAL COMPANY (US) 1990-07-25 EP claimed