Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 10/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095172 | 0.76 | CCR5 (0.42) | CCR5 | |
| SCHEMBL7732703 | 0.71 | CCR5 (0.53) | CCR5 | |
| SCHEMBL994551 | 0.71 | MAPT (0.40) | ATMTDP1ALDH1A1MAPTHPGD | |
| SCHEMBL994549 | 0.71 | MAPT (0.40) | ATMTDP1ALDH1A1MAPTHPGD | |
| SCHEMBL6767786 | 0.70 | KDM4E (0.43) | ATMCCR5TDP1ALDH1A1MAPT | |
| SCHEMBL5724304 | 0.70 | ALDH1A1 (0.47) | TDP1ALDH1A1MAPTHPGDBCHE | |
| SCHEMBL10639614 | 0.70 | SMN1; SMN2 (0.47) | TDP1ALDH1A1MAPTHPGD | |
| Trifluoroacetic Acid SCHEMBL8095167 | 0.69 | SLC6A2 (0.41) | CCR5ALDH1A1KCNJ1 | |
| SCHEMBL8439868 | 0.68 | EPHX1 (0.45) | TDP1KCNJ1 | |
| SCHEMBL8438723 | 0.68 | EPHX1 (0.45) | TDP1KCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |