Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | XDH | P47989 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL322220 | 0.84 | RAB9A (0.56) | SMN1; SMN2RAB9ACCR5F2PRMT5 | |
| SCHEMBL1316322 | 0.81 | FOLH1 (0.60) | XDHALDH1A1KDM4E | |
| SCHEMBL24244911 | 0.80 | GSTP1 (0.54) | SMN1; SMN2RAB9ALMNAPTPN1MAPT | |
| SCHEMBL8426083 | 0.79 | IGF1R (0.51) | XDHLTA4HMAPK14ALDH1A1TSHR | |
| SCHEMBL17488404 | 0.79 | RAB9A (0.51) | SMN1; SMN2RAB9ACCR5F2ALDH1A1 | |
| SCHEMBL30835101 | 0.77 | RAB9A (0.59) | SMN1; SMN2RAB9ACCR5ALDH1A1LMNA | |
| SCHEMBL7898169 | 0.77 | RAB9A (0.59) | SMN1; SMN2RAB9ACCR5ALDH1A1LMNA | |
| SCHEMBL19398436 | 0.77 | F2 (0.49) | SMN1; SMN2RAB9AF2KDM4ENPC1 | |
| SCHEMBL528926 | 0.76 | RAB9A (0.61) | SMN1; SMN2RAB9AF2KDM4ELMNA | |
| SCHEMBL8982918 | 0.76 | RAB9A (0.57) | SMN1; SMN2RAB9ACCR5F2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872301-A | Bifunctional precursors for the preparation of liquid crystals | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |
| US-5686608-A | Process for cross-coupling aromatic boron compounds with aromatic halogen compounds or perfluoroalkylsulfonates | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-11 | — | — | US | disclosed |