Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL322220 | 0.91 | RAB9A (0.56) | RAB9ASMN1; SMN2MAPTL3MBTL1TDP1 | |
| SCHEMBL19398436 | 0.88 | F2 (0.49) | RAB9ASMN1; SMN2MAPTL3MBTL1TDP1 | |
| SCHEMBL1855654 | 0.87 | MAPT (0.56) | RAB9ASMN1; SMN2MAPTL3MBTL1TDP1 | |
| SCHEMBL24244911 | 0.86 | GSTP1 (0.54) | RAB9ASMN1; SMN2MAPTL3MBTL1MAOB | |
| SCHEMBL10093047 | 0.82 | ERN1 (0.55) | MAPTL3MBTL1TDP1MAPK1MRGPRX4 | |
| SCHEMBL1994146 | 0.80 | RAB9A (0.52) | RAB9ASMN1; SMN2MAPTL3MBTL1TDP1 | |
| SCHEMBL8440333 | 0.79 | SMN1; SMN2 (0.51) | RAB9ASMN1; SMN2MAPTF2NPC1 | |
| SCHEMBL1756349 | 0.78 | ABCC4 (0.58) | RAB9ASMN1; SMN2MRGPRX4PTPN1LMNA | |
| SCHEMBL17488403 | 0.78 | GSTP1 (0.56) | MAPK1MAOBMCL1LMNACYP1A2 | |
| Toluene SCHEMBL27793177 | 0.78 | L3MBTL1 (0.50) | RAB9ASMN1; SMN2MAPTL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938229-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2018-04-10 | — | — | US | disclosed |
| US-20160032189-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160032189-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | VCL, ILK, LCP1 | RAB9A 579/4885SMN1; SMN2 2420/4885MAPT 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.