Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 3/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438588 | 0.77 | HCAR2 (0.36) | — | |
| SCHEMBL18243444 | 0.77 | CHRM5 (0.52) | CYP1A2POLBCYP2C19 | |
| SCHEMBL15741728 | 0.76 | TSHR (0.44) | TSHRAHRTP53CYP3A4 | |
| SCHEMBL9967774 | 0.75 | AHR (0.48) | TSHRAHRGABRA1GABRB1 | |
| SCHEMBL3086641 | 0.74 | HSD17B10 (0.46) | AHRCYP1A2 | |
| SCHEMBL18378645 | 0.72 | ALDH1A1 (0.39) | TSHRAHRGABRA1GABRB1TP53 | |
| SCHEMBL19514696 | 0.71 | TSHR (0.53) | TSHRAHRTP53CYP3A4 | |
| 1,3,5-Trichlorobenzene SCHEMBL28732101 | 0.70 | TSHR (0.61) | TSHRAHRGABRA1GABRB1TP53 | |
| SCHEMBL1547286 | 0.69 | TSHR (0.50) | TSHRAHRTP53CYP3A4 | |
| SCHEMBL21470189 | 0.68 | TSHR (0.42) | TSHRAHRGABRA1GABRB1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968947-A | INSECTICIDES, ACARICIDES, NEMATOCIDES | ZENECA LIMITED (GB) | 1999-10-19 | — | — | US | disclosed |